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- [1] Epigenetic clocks provide clues to the mystery of uterine ageingHUMAN REPRODUCTION UPDATE, 2023, 29 (03) : 259 - 271Deryabin, Pavel, I论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Sci, Mech Cellular Senescence Grp, Inst Cytol, St Petersburg, Russia Russian Acad Sci, Mech Cellular Senescence Grp, Inst Cytol, St Petersburg, RussiaBorodkina, Aleksandra, V论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Sci, Mech Cellular Senescence Grp, Inst Cytol, St Petersburg, Russia Russian Acad Sci, Inst Cytol, Mech Cellular Senescence Grp, Tikhoretsky Ave 4, St Petersburg 194064, Russia Russian Acad Sci, Mech Cellular Senescence Grp, Inst Cytol, St Petersburg, Russia
- [2] Epigenetic ageing clocks: statistical methods and emerging computational challengesNATURE REVIEWS GENETICS, 2025, : 350 - 368Teschendorff, Andrew E.论文数: 0 引用数: 0 h-index: 0机构: Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Chinese Acad Sci, CAS Key Lab Computat Biol, Shanghai, Peoples R China Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Chinese Acad Sci, CAS Key Lab Computat Biol, Shanghai, Peoples R ChinaHorvath, Steve论文数: 0 引用数: 0 h-index: 0机构: Altos Labs, Cambridge, England Univ Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Chinese Acad Sci, CAS Key Lab Computat Biol, Shanghai, Peoples R China
- [3] Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageingJOURNAL OF INTERNAL MEDICINE, 2024, 295 (01) : 79 - 90Neytchev, Ognian论文数: 0 引用数: 0 h-index: 0机构: Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, Scotland Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, Scotland论文数: 引用数: h-index:机构:Witasp, Anna论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandNordfors, Louise论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandQureshi, Abdul Rashid论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandIseri, Ken论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandMorohoshi, Hokuto论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandSelman, Colin论文数: 0 引用数: 0 h-index: 0机构: Univ Glasgow, Inst Biodivers Anim Hlth & Comparat Med, Coll Med Vet & Life Sci, Glasgow, Scotland Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandEbert, Thomas论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandKublickiene, Karolina论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandStenvinkel, Peter论文数: 0 引用数: 0 h-index: 0机构: Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Renal Med, Stockholm, Sweden Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, ScotlandShiels, Paul G.论文数: 0 引用数: 0 h-index: 0机构: Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, Scotland Univ Glasgow, Coll Med Vet & Life Sci, Sch Mol Biosci, Glasgow, Scotland
- [4] Epigenetic ClocksEVOLUTIONARY ANTHROPOLOGY, 2018, 27 (06): : 256 - 260Guevara, Elaine E.论文数: 0 引用数: 0 h-index: 0机构: George Washington Univ, Dept Anthropol, Ctr Adv Study Human Paleobiol, Washington, DC 20052 USA Yale Univ, Dept Anthropol, New Haven, CT 06520 USA George Washington Univ, Dept Anthropol, Ctr Adv Study Human Paleobiol, Washington, DC 20052 USALawler, Richard R.论文数: 0 引用数: 0 h-index: 0机构: James Madison Univ, Dept Sociol & Anthropol, Harrisonburg, VA 22807 USA George Washington Univ, Dept Anthropol, Ctr Adv Study Human Paleobiol, Washington, DC 20052 USA
- [5] EPIGENETIC CLOCKS SUGGEST ACCELERATED AGEING IN ISOLATED REM SLEEP BEHAVIOR DISORDER PATIENTSSLEEP MEDICINE, 2022, 100 : S227 - S227Baldelli, L.论文数: 0 引用数: 0 h-index: 0机构: Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, ItalyBacalini, M. G.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ist Sci Neurol Bologna, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, ItalyPirazzini, C.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ist Sci Neurol Bologna, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, ItalySambati, L.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ist Sci Neurol Bologna, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, ItalyMignani, F.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ist Sci Neurol Bologna, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, ItalyGuaraldi, P.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ist Sci Neurol Bologna, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, Italy论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Franceschi, C.论文数: 0 引用数: 0 h-index: 0机构: IRCCS Ist Sci Neurol Bologna, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, ItalyProvini, F.论文数: 0 引用数: 0 h-index: 0机构: Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, Italy IRCCS Ist Sci Neurol Bologna, Bologna, Italy Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Bologna, Italy
- [6] Blood and skeletal muscle ageing determined by epigenetic clocks and their associations with physical activity and functioningClinical Epigenetics, 2021, 13Elina Sillanpää论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesAino Heikkinen论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesAnna Kankaanpää论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesAini Paavilainen论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesUrho M. Kujala论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesTuija H. Tammelin论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesVuokko Kovanen论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesSarianna Sipilä论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesKirsi H. Pietiläinen论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesJaakko Kaprio论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesMiina Ollikainen论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health SciencesEija K. Laakkonen论文数: 0 引用数: 0 h-index: 0机构: University of Jyväskylä,Gerontology Research Center, Faculty of Sport and Health Sciences
- [7] Blood and skeletal muscle ageing determined by epigenetic clocks and their associations with physical activity and functioningCLINICAL EPIGENETICS, 2021, 13 (01)Sillanpaa, Elina论文数: 0 引用数: 0 h-index: 0机构: Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, Finland Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandHeikkinen, Aino论文数: 0 引用数: 0 h-index: 0机构: Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland Univ Helsinki, Dept Publ Hlth, Helsinki, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandKankaanpaa, Anna论文数: 0 引用数: 0 h-index: 0机构: Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandPaavilainen, Aini论文数: 0 引用数: 0 h-index: 0机构: Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandKujala, Urho M.论文数: 0 引用数: 0 h-index: 0机构: Univ Jyvaskyla, Fac Sport & Hlth Sci, Jyvaskyla, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandTammelin, Tuija H.论文数: 0 引用数: 0 h-index: 0机构: LIKES Res Ctr Phys Activ & Hlth, Jyvaskyla, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandKovanen, Vuokko论文数: 0 引用数: 0 h-index: 0机构: Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandSipila, Sarianna论文数: 0 引用数: 0 h-index: 0机构: Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandPietilainen, Kirsi H.论文数: 0 引用数: 0 h-index: 0机构: Univ Helsinki, Res Program Clin & Mol Metab, Obes Res Unit, Fac Med, Helsinki, Finland Helsinki Univ Hosp, Obes Ctr, Endocrinol Abdominal Ctr, Helsinki, Finland Univ Helsinki, Helsinki, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandKaprio, Jaakko论文数: 0 引用数: 0 h-index: 0机构: Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandOllikainen, Miina论文数: 0 引用数: 0 h-index: 0机构: Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland Univ Helsinki, Dept Publ Hlth, Helsinki, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, FinlandLaakkonen, Eija K.论文数: 0 引用数: 0 h-index: 0机构: Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, Finland Univ Jyvaskyla, Fac Sport & Hlth Sci, Gerontol Res Ctr, POB 35 VIV, Jyvaskyla 40014, Finland
- [8] Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volumeGeroScience, 2022, 44 : 1807 - 1823Lidija Milicic论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthMichael Vacher论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthTenielle Porter论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthVincent Doré论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthSamantha C. Burnham论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthPierrick Bourgeat论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthRosita Shishegar论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthJames Doecke论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthNicola J. Armstrong论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthRick Tankard论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthPaul Maruff论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthColin L. Masters论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthChristopher C. Rowe论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthVictor L. Villemagne论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision HealthSimon M. Laws论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan University,Centre for Precision Health
- [9] Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volumeGEROSCIENCE, 2022, 44 (03) : 1807 - 1823Milicic, Lidija论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia Edith Cowan Univ, Sch Med & Hlth Sci, Collaborat Genom & Translat Grp, Joondalup, WA 6027, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaVacher, Michael论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia Edith Cowan Univ, Sch Med & Hlth Sci, Collaborat Genom & Translat Grp, Joondalup, WA 6027, Australia Australian E Hlth Res Ctr, CSIRO Hlth & Biosecur, Floreat, WA 6014, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia论文数: 引用数: h-index:机构:Dore, Vincent论文数: 0 引用数: 0 h-index: 0机构: CSIRO, Australian Hlth Res Ctr, Parkville, Vic 3052, Australia Austin Hlth, Dept Mol Imaging & Therapy, Heidelberg, Vic, Australia Austin Hlth, Ctr PET, Heidelberg, Vic, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaBurnham, Samantha C.论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia CSIRO, Australian Hlth Res Ctr, Parkville, Vic 3052, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaBourgeat, Pierrick论文数: 0 引用数: 0 h-index: 0机构: CSIRO, Australian Hlth Res Ctr, Herston, Qld 4029, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaShishegar, Rosita论文数: 0 引用数: 0 h-index: 0机构: CSIRO, Australian Hlth Res Ctr, Parkville, Vic 3052, Australia Monash Univ, Sch Psychol Sci, Melbourne, Vic, Australia Monash Univ, Turner Inst Brain & Mental Hlth, Melbourne, Vic, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaDoecke, James论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia CSIRO, Australian Hlth Res Ctr, Herston, Qld 4029, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaArmstrong, Nicola J.论文数: 0 引用数: 0 h-index: 0机构: Curtin Univ, Dept Math & Stat, Bentley, WA, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaTankard, Rick论文数: 0 引用数: 0 h-index: 0机构: Murdoch Univ, Sch Math & Stat, Perth, WA, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia论文数: 引用数: h-index:机构:Masters, Colin L.论文数: 0 引用数: 0 h-index: 0机构: Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Parkville, Vic 3052, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaRowe, Christopher C.论文数: 0 引用数: 0 h-index: 0机构: Austin Hlth, Dept Mol Imaging & Therapy, Heidelberg, Vic, Australia Austin Hlth, Ctr PET, Heidelberg, Vic, Australia Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Parkville, Vic 3052, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaVillemagne, Victor L.论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia Austin Hlth, Dept Mol Imaging & Therapy, Heidelberg, Vic, Australia Austin Hlth, Ctr PET, Heidelberg, Vic, Australia Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, AustraliaLaws, Simon M.论文数: 0 引用数: 0 h-index: 0机构: Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia Edith Cowan Univ, Sch Med & Hlth Sci, Collaborat Genom & Translat Grp, Joondalup, WA 6027, Australia Curtin Univ, Curtin Hlth Innovat Res Inst, Fac Hlth Sci, Sch Pharm & Biomed Sci, Bentley, WA 6102, Australia Edith Cowan Univ, Ctr Precis Hlth, 270 Joondalup Dr, Joondalup, WA 6027, Australia
- [10] Epigenetic drift, epigenetic clocks and cancer riskEPIGENOMICS, 2016, 8 (05) : 705 - 719Zheng, Shijie C.论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, CAS Key Lab Computat Biol, Shanghai 200031, Peoples R China Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China Chinese Acad Sci, Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, CAS Key Lab Computat Biol, Shanghai 200031, Peoples R ChinaWidschwendter, Martin论文数: 0 引用数: 0 h-index: 0机构: UCL, Dept Womens Canc, 74 Huntley St, London WC1E 6AU, England Chinese Acad Sci, Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, CAS Key Lab Computat Biol, Shanghai 200031, Peoples R ChinaTeschendorff, Andrew E.论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, CAS Key Lab Computat Biol, Shanghai 200031, Peoples R China UCL, Dept Womens Canc, 74 Huntley St, London WC1E 6AU, England UCL, UCL Canc Inst, Stat Canc Genom, 72 Huntley St, London WC1E 6BT, England Chinese Acad Sci, Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, CAS Key Lab Computat Biol, Shanghai 200031, Peoples R China