Halogen Atom Transfer-Induced Homolysis of C-F Bonds by the Excited-State Boryl Radical

被引：14

作者：

Koo, Jangwoo ^{[1
]}

Kim, Weonjeong ^{[1
]}

Jhun, Byung Hak ^{[2
]}

Park, Subin ^{[1
]}

Song, Dayoon ^{[2
]}

You, Youngmin ^{[2
]}

Lee, Hong Geun ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Nat Sci, Dept Chem, Seoul 08826, South Korea

[2] Yonsei Univ, Dept Chem & Biomol Engn, Seoul 03722, South Korea

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2024年 / 146卷 / 33期

基金：

新加坡国家研究基金会;

关键词：

N-HETEROCYCLIC CARBENES; SODIUM-BOROHYDRIDE; BORANE COMPLEXES; LEWIS-BASES; GENERATION; REACTIVITY; ACTIVATION; CATALYSIS; FLUORINE; ALKENES;

D O I：

10.1021/jacs.4c06337

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel reactivity toward C-F bond functionalization has been developed, which could be designated as fluorine atom transfer (FAT). A photoexcited state of an N-heterocyclic carbene-ligated boryl radical exhibits a transcendent reactivity, capable of activating chemically inert carbon-fluorine bonds through homolysis. Combined experimental and computational studies suggest that the ligated boryl radical species directly abstracts a fluorine atom from the organofluoride substrates to provide valuable carbon-centered radicals.

引用

页码：22874 / 22880

页数：7

共 16 条

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