Reversibility of a critical intraventricular conduction delay under flecainide and lacosamide by sodium bicarbonate

被引：0
|
作者：
Gallinger, Anja [1 ]
Osei-Davies, Rahman [1 ]
Hennersdorf, F. [1 ]
机构：
[1] Schon Klin Eilbek, Klin Innere Med Kardiol & Angiol, Dehnhaide 120, D-22081 Hamburg, Germany
来源：
INNERE MEDIZIN | 2024年 / 65卷 / 12期
关键词：
Exit block; Voltage-gated sodium channels; Sodium channel blockers; Wide QRS; Additive side effect of medications;
D O I：
10.1007/s00108-024-01768-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The case of a 72-year-old female patient with arrhythmogenic syncope associated with a combination therapy of flecainide and lacosamide is presented. The authors believe in an additive effect of both drugs on myocardial voltage-gated sodium channels with extraordinary QRS widening, exit block with temporary pacing and complete reversibility through infusion of sodium bicarbonate as bail-out therapy.
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页码：1266 / 1269
页数：4
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