Coronary Microvascular Dysfunction: A Guide for Clinicians

被引：4

作者：

Smati, Hannah ^{[1
]}

Sellke, Frank W. ^{[2
]}

Bourque, Jamieson M. ^{[3
]}

Qadeer, Yusuf Kamran ^{[4
]}

Niccoli, Giampaolo ^{[5
,6
]}

Montone, Rocco A. ^{[7
]}

Krittanawong, Chayakrit ^{[8
,9
]}

机构：

[1] Baylor Coll Med, Dept Med, Houston, TX USA

[2] Brown Univ, Warren Alpert Sch Med, Cardiovasc Res Ctr, Div Cardiothorac Surg, Providence, RI USA

[3] Univ Virginia Hlth Syst, Div Cardiovasc Med & Radiol, Charlottesville, VA USA

[4] Henry Ford Hosp, Dept Med, Div Cardiol, Detroit, MI USA

[5] Univ Parma, Dept Med & Surg, Parma, Italy

[6] Parma Univ Hosp, Div Cardiol, Parma, Italy

[7] Fdn Policlin Univ A Gemelli IRCCS, Dept Cardiovasc Med, Rome, Italy

[8] NYU Langone Hlth, Cardiol Div, New York, NY USA

[9] NYU, Sch Med, New York, NY USA

来源：

AMERICAN JOURNAL OF MEDICINE | 2024年 / 137卷 / 09期

基金：

美国国家卫生研究院;

关键词：

CMD; Coronary flow reserve; Coronary microvascular dysfunction; Index of Microcirculatory Resistance; CONVERTING ENZYME-INHIBITION; MYOCARDIAL BLOOD-FLOW; OF-THE-ART; CARDIAC REHABILITATION; VASOMOTOR DYSFUNCTION; ENDOTHELIAL FUNCTION; HEART-FAILURE; SYNDROME-X; PERFUSION; RESERVE;

D O I：

10.1016/j.amjmed.2024.04.035

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Dysfunction of the coronary microvasculature has become increasingly recognized as an important mechanism of myocardial ischemia in patients without obstructive coronary artery disease. The causes and management of coronary microvascular dysfunction remain poorly understood and are still largely based on extrapolation of epicardial coronary artery disease data. Quantification of myocardial blood flow and flow reserve have improved diagnosis, though important questions remain. In this review, we explain current understanding of the spectrum of pathophysiology of coronary microvascular dysfunction, summarize current diagnostic techniques to assess for coronary microvascular dysfunction, and appraise the limited data on management options specifically for patients with coronary microvascular dysfunction. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

引用

页码：810 / 817

页数：8

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