Microfluidic Detection of SPIONs and Co-Ferrite Ferrofluid Using Amorphous Wire Magneto-Impedance Sensor

被引:1
|
作者
Barrera, Gabriele [1 ]
Celegato, Federica [1 ]
Vassallo, Marta [1 ]
Martella, Daniele [2 ,3 ]
Coisson, Marco [1 ]
Olivetti, Elena S. [1 ]
Martino, Luca [1 ]
Sozeri, Huseyin [4 ]
Manzin, Alessandra [1 ]
Tiberto, Paola [1 ]
机构
[1] Ist Nazl Ric Metrolog INRiM, Dept Adv Mat Metrol & Life Sci, Str Cacce 91, I-10135 Turin, Italy
[2] European Lab Non Linear Spect LENS, Via N Carrara 1, I-50019 Florence, Italy
[3] Univ Florence, Dept Chem Ugo Schiff, Via Lastruccia 3-13, I-50019 Florence, Italy
[4] TUBITAK Ulusal Metrol Enstitusu UME, Magnet Lab, TR-41470 Kocaeli, Turkiye
关键词
magneto-impedance sensor; magnetic nanoparticles; magnetic wire; SPIONs; Co-ferrite; microfluidic system; GIANT-MAGNETOIMPEDANCE; SENSITIVE ELEMENT; NANOPARTICLES; BIOSENSOR; SIZE; STEP;
D O I
10.3390/s24154902
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The detection of magnetic nanoparticles in a liquid medium and the quantification of their concentration have the potential to improve the efficiency of several relevant applications in different fields, including medicine, environmental remediation, and mechanical engineering. To this end, sensors based on the magneto-impedance effect have attracted much attention due to their high sensitivity to the stray magnetic field generated by magnetic nanoparticles, their simple fabrication process, and their relatively low cost. To improve the sensitivity of these sensors, a multidisciplinary approach is required to study a wide range of soft magnetic materials as sensing elements and to customize the magnetic properties of nanoparticles. The combination of magneto-impedance sensors with ad hoc microfluidic systems favors the design of integrated portable devices with high specificity towards magnetic ferrofluids, allowing the use of very small sample volumes and making measurements faster and more reliable. In this work, a magneto-impedance sensor based on an amorphous Fe73.5Nb3Cu1Si13.5B9 wire as the sensing element is integrated into a customized millifluidic chip. The sensor detects the presence of magnetic nanoparticles in the ferrofluid and distinguishes the different stray fields generated by single-domain superparamagnetic iron oxide nanoparticles or magnetically blocked Co-ferrite nanoparticles.
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页数:14
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