Endoplasmic reticulum-mitochondria lockdown in Wolfram syndrome

被引：0

作者：

Filadi, Riccardo ^{[1
,2
]}

Pizzo, Paola ^{[1
,2
,3
]}

机构：

[1] Univ Padua, Dept Biomed Sci, Padua, Italy

[2] Natl Res Council CNR, Inst Neurosci, Padua, Italy

[3] Univ Padua, Ctr Studi Neurodegeneraz CESNE, Padua, Italy

来源：

CELL CALCIUM | 2024年 / 124卷

关键词：

Endoplasmic reticulum; Mitochondria; Wolfram syndrome; ER-mitochondria contacts; Calcium signaling;

D O I：

10.1016/j.ceca.2024.102955

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Wolfram syndrome (WS) is an incurable autosomal recessive disorder originally described as a mitochondriopathy. In a recent work, Liiv and colleagues found that an impaired endoplasmic reticulum (ER)-to-mitochondria calcium shuttling underlies mitochondrial dysfunction in WS models.

引用

页数：3

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