Fatal hyperpyrexia caused by xylazine: a case report

被引：1
|
作者：
Dai, Ping [1 ]
Chen, Yanqing [2 ]
Luo, Xianqin [3 ]
Zhou, Zhiqiang [1 ,4 ]
Shi, Mengdi [1 ,4 ]
Genjiafu, Aerbusili [1 ,4 ]
Jian, Xiangdong [1 ,4 ]
机构：
[1] Shandong Univ, Qilu Hosp, Dept Poisoning & Occupat Dis Emergency med, Cheeloo Coll Med, Jinan, Peoples R China
[2] Huangdao Dist Cent Hosp, Emergency Dept, Qingdao, Peoples R China
[3] Suining Cent Hosp, Emergency Dept, Suining, Peoples R China
[4] Shandong Univ, Cheeloo Coll Med, Sch Publ Hlth, Dept Occupat & Environm Hlth, Jinan, Peoples R China
来源：
FRONTIERS IN PHARMACOLOGY | 2024年 / 15卷
关键词：
drugs; human; hyperpyrexia; poisoning; xylazine; SEVERE INTOXICATION; AGONISTS; ABUSE; DRUG;
D O I：
10.3389/fphar.2024.1437960
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Xylazine is used in veterinary medicine as a sedative, analgesic, and muscle relaxant. However, in recent decades, it has frequently been detected in illicit drugs. Xylazine poisoning is characterized by depression of the central nervous and cardiovascular systems. Herein, we present a case of a 41-year-old man who not only had severe depression of the central nervous and cardiovascular systems, but also developed hyperpyrexia during the treatment of xylazine poisoning, which led to his death 3 days after poisoning. This case indicates that, in addition to its other effects, xylazine may also cause hyperthermia, which has not yet been reported in humans.
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页数：5
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