Diagnostic and Therapeutic Approaches for Heart Failure in Long-Term Survivors of Childhood Cancer

被引：0
|
作者：
Fernandez-Aviles, Consuelo [1 ,2 ]
Gonzalez-Manzanares, Rafael [1 ,2 ,3 ]
Ojeda, Soledad [1 ,2 ,3 ,4 ]
Castillo, Juan C. [1 ,2 ,3 ]
Robles-Mezcua, Ainhoa [3 ,5 ,6 ]
Anguita, Manuel [1 ,2 ,3 ]
Mesa, Dolores [1 ,2 ,3 ]
Pan, Manuel [1 ,2 ,3 ,4 ]
机构：
[1] Reina Sofia Univ Hosp, Cardiol Unit, Cordoba 14004, Spain
[2] Inst Maimonides Invest Biomed Cordoba IMIBIC, Cordoba 14004, Spain
[3] Ctr Invest Biomed Red Enfermedades Cardiovasc CIBE, Madrid 28029, Spain
[4] Univ Cordoba, Dept Ciencias Med & Quirurg, Cordoba 14004, Spain
[5] Univ Virgen Victoria, Hosp Clin, Malaga 29010, Spain
[6] Univ Malaga, IBIMA Plataforma BIONAND, Malaga 29071, Spain
来源：
BIOMEDICINES | 2024年 / 12卷 / 08期
关键词：
heart failure therapy; cardiotoxicity; long-term survivors; childhood cancer; VENTRICULAR SYSTOLIC FUNCTION; CARDIAC MAGNETIC-RESONANCE; ADULT SURVIVORS; 5-YEAR SURVIVORS; BREAST-CANCER; ATRIAL-FIBRILLATION; FOLLOW-UP; CARDIOTOXICITY; CHEMOTHERAPY; DYSFUNCTION;
D O I：
10.3390/biomedicines12081875
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The improvement in survival rates in pediatric malignancies has led to an increase in the number of cancer survivors who are at risk of developing cardiotoxicity and heart failure. Cardiac dysfunction in these patients can occur asymptomatically, and the diagnosis in a symptomatic phase is associated with reduced treatment response and worse prognosis. For this reason, it is essential to establish protocols to follow up on these patients and identify those at risk of cardiotoxicity in order to start early and effective therapies. This review aims to summarize the latest findings in the diagnosis and treatment of cancer therapy-related cardiac disease in long-term survivors of childhood cancer, with a focus on heart failure.
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页数：13
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