Biochemical assessment of amniotic membrane extract for optimal application in regenerative medicine

被引：1
|
作者：
Bedewy, Nourhan [1 ]
Elbordiny, Magdy [1 ]
Swelem, Manal [2 ]
Eldabah, Nermeen [1 ]
机构：
[1] Alexandria Univ, Dept Clin & Chem Pathol, Alexandria, Egypt
[2] Alexandria Univ, Dept Obstet & Gynecol, Alexandria, Egypt
来源：
ALEXANDRIA JOURNAL OF MEDICINE | 2024年 / 60卷 / 01期
关键词：
Amniotic membrane; subregional variances; regenerative medicine; GROWTH-FACTOR; BETA;
D O I：
10.1080/20905068.2024.2380213
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
ObjectiveAmniotic membrane (AM) extract is a promising tool in regenerative medicine, which offers similar therapeutic effects as intact AM but with a simpler and safer approach. AM displays several subregional variances.MethodThe quantitative analysis of hepatocyte growth factor (HGF) and transforming growth factor-beta 1 (TGF-beta 1) in placental and reflected AM sections were assayed by enzyme-linked immunosorbent assay.ResultsDetection of high levels of HGF and TGF-beta 1 with variation in concentration between the placental and reflected portions of the same membrane.ConclusionUnderstanding AM subregional variations would optimize AM extract preparation for specific regenerative medicine therapies.
引用
收藏
页码：215 / 221
页数：7
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