INVESTIGATION OF REGORAFENIB TUMOR SENSITIVITY AND UNDERLYING TREATMENT INDUCED MOLECULAR MECHANISMS IN GLIOBLASTOMA RECURRENT TUMORS

被引:0
|
作者
Morelli, M. [1 ]
Lessi, F. [1 ]
Giacomarra, M. [1 ]
Marranci, A. [1 ]
Menicagli, M. [1 ]
Santonocito, O. S. [2 ]
Aretini, P. [1 ]
Pasqualetti, F. [3 ]
Di Stefano, A. L. [2 ]
Franceschi, S. [1 ]
Mazzanti, C. M. [1 ]
机构
[1] Fdn Pisana Sci, Pisa, Italy
[2] Spedali Riuniti Livorno, Neurosurg Dept, Livorno, Italy
[3] Univ Oxford, Dept Oncol, Oxford, England
关键词
D O I
10.1093/neuonc/noad137.406
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P17.16.B
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Exploring Regorafenib Responsiveness and Uncovering Molecular Mechanisms in Recurrent Glioblastoma Tumors through Longitudinal In Vitro Sampling
    Morelli, Mariangela
    Lessi, Francesca
    Franceschi, Sara
    Ferri, Gianmarco
    Giacomarra, Manuel
    Menicagli, Michele
    Gambacciani, Carlo
    Pieri, Francesco
    Pasqualetti, Francesco
    Montemurro, Nicola
    Aretini, Paolo
    Santonocito, Orazio Santo
    Di Stefano, Anna Luisa
    Mazzanti, Chiara Maria
    CELLS, 2024, 13 (06)
  • [2] A STUDY OF CLINICAL AND MOLECULAR PROGNOSTIC FACTORS FOR RESPONSE TO REGORAFENIB IN RECURRENT GLIOBLASTOMA.
    Chiesa, Silvia
    Mangraviti, Antonella
    Martini, Maurizio
    Cenci, Tonia
    Mazzarella, Ciro
    Gaudino, Simona
    Bracci, Serena
    Martino, Antonella
    Della Pepa, Giuseppe M.
    Offi, Martina
    Gessi, Marco
    Russo, Rosellina
    Martucci, Matia
    Bartoli, Francesco Beghella
    Di Bonaventura, Rina
    Larocca, Luigi M.
    Lauretti, Liverana
    Olivi, Alessandro
    Pallini, Roberto
    Balducci, Mario
    D'Alessandris, Quintino Giorgio
    NEURO-ONCOLOGY, 2022, 24 : 12 - 12
  • [3] Mapping of molecular landscape underlying drug resistance and recurrence in glioblastoma: Paired analysis of primary and recurrent tumors
    Megova, Magdalena Houdova
    Sporikova, Zuzana
    Trojanec, Radek
    Kalita, Ondrej
    Vrbkova, Jana
    Drabek, Jiri
    Koudelakova, Vladimira
    Hajduch, Marian
    CANCER RESEARCH, 2018, 78 (13)
  • [4] Molecular mechanisms underlying tumor dormancy
    Almog, Nava
    CANCER LETTERS, 2010, 294 (02) : 139 - 146
  • [5] Regorafenib and glioblastoma: a literature review of preclinical studies, molecular mechanisms and clinical effectiveness
    Mongiardi, Maria Patrizia
    Pallini, Roberto
    D'Alessandris, Quintino Giorgio
    Levi, Andrea
    Falchetti, Maria Laura
    EXPERT REVIEWS IN MOLECULAR MEDICINE, 2024, 26
  • [6] Molecular Mechanisms Underlying Oxidation Sensitivity of VRAC
    Bertelli, Sara
    Pusch, Michael
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 483A - 483A
  • [7] MOLECULAR PROFILING OF PRIMARY VERSUS RECURRENT GLIOBLASTOMA BRAIN TUMOR STEM CELLS UNCOVERS SIGNALING MECHANISMS THAT PROMOTE THE AGGRESSIVENESS OF RECURRENT GLIOBLASTOMA.
    Heemskerk, Kyle
    Hao, Xiaoguang
    Cseh, Orsolya
    Luchman, H. Artee
    Weiss, Samuel
    NEURO-ONCOLOGY, 2022, 24 : 31 - 31
  • [8] Underlying mechanisms and management strategies for regorafenib-induced toxicity in hepatocellular carcinoma
    Cheng, Mengting
    Tao, Xinyu
    Wang, Fei
    Shen, Nonger
    Xu, Zhifei
    Hu, Yuhuai
    Huang, Ping
    Luo, Peihua
    He, Qiaojun
    Zhang, Yiwen
    Yan, Fangjie
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2024, 20 (09) : 907 - 922
  • [9] Cellular and molecular mechanisms underlying IL-12-induced tumor regression
    Fujiwara, H
    Clark, SC
    Hamaoka, T
    INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE, 1996, 795 : 294 - 309
  • [10] MOLECULAR MECHANISMS UNDERLYING THE ANTITUMOR EFFECT OF FASUDIL ON GLIOBLASTOMA CELLS
    Nakabayashi, H.
    Shimizu, K.
    NEURO-ONCOLOGY, 2012, 14 : 17 - 17