Automated software-derived supine baseline impedance is highly correlated with manual nocturnal baseline impedance for the diagnosis of GERD

Background Mean nocturnal baseline impedance (MNBI) can improve diagnostic accuracy for gastroesophageal reflux disease (GERD), but must be manually calculated and is not routinely reported. We aimed to determine how automated software-derived mean supine baseline impedance (MSBI), a potential novel GERD metric, is related to MNBI. Methods Consecutively obtained pH-impedance studies were assessed. Manually extracted MNBI was compared to MSBI using paired t-test and Spearman's correlations. Key Results The correlation between MNBI and MSBI was very high (rho = 0.966, p < 0.01). Conclusions & Inferences The ease of acquisition and correlation with MNBI warrant the routine clinical use and reporting of MSBI with pH-impedance studies.