PLK1 inhibition overcomes PARP inhibitor resistance in triple-negative breast cancer

被引:0
|
作者
Siraj, Abdul K.
Poyil, Pratheesh Kumar
Padmaja, Divya
Parvathareddy, Sandeep Kumar
Alobaisi, Khadija
Begum, Rafia
Almalik, Osama
Al-Dayel, Fouad
Al-Kuraya, Khawla S.
机构
关键词
D O I
10.1158/1538-7445.AM2024-7205
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
7205
引用
收藏
页数:2
相关论文
共 50 条
  • [1] PLK1 and PARP positively correlate in Middle Eastern breast cancer and their combined inhibition overcomes PARP inhibitor resistance in triple negative breast cancer
    Siraj, Abdul K.
    Poyil, Pratheesh Kumar
    Padmaja, Divya
    Parvathareddy, Sandeep Kumar
    Alobaisi, Khadija
    Thangavel, Saravanan
    Diaz, Roxanne
    Begum, Rafia
    Almalik, Osama
    Al-Dayel, Fouad
    Al-Kuraya, Khawla S.
    FRONTIERS IN ONCOLOGY, 2024, 13
  • [2] Therapeutic potential of PLK1 inhibition in triple-negative breast cancer
    Ueda, Ai
    Oikawa, Keiki
    Fujita, Koji
    Ishikawa, Akio
    Sato, Eiichi
    Ishikawa, Takashi
    Kuroda, Masahiko
    Kanekura, Kohsuke
    LABORATORY INVESTIGATION, 2019, 99 (09) : 1275 - 1286
  • [3] Inhibition of the mitotic kinase PLK1 overcomes therapeutic resistance to BET inhibitors in triple negative breast cancer
    Nieto-Jimenez, Cristina
    Galan-Moya, Eva M.
    Corrales-Sanchez, Veronica
    del Mar Noblejas-Lopez, Maria
    Burgos, Miguel
    Domingo, Beatriz
    Montero, Juan Carlos
    Gomez-Juarez, Monica
    Granada Picazo-Martinez, Maria
    Esparis-Ogando, Azucena
    Pandiella, Atanasio
    Ocana, Alberto
    CANCER LETTERS, 2020, 491 : 50 - 59
  • [4] Combining PARP inhibition with the polo-like kinase 1 (PLK1) inhibitor onvansertib overcomes PARP inhibitor resistance
    Chiappa, Michela
    Guffanti, Federica
    Decio, Alessandra
    Aliverti, Alessandro
    Ricci, Francesca
    Scanziani, Eugenio
    Camin, Federica
    Craparotta, Ilaria
    Barbera, Maria Chiara
    Bolis, Marco
    Ridinger, Maya
    Damia, Giovanna
    CANCER RESEARCH, 2022, 82 (12)
  • [5] Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer
    Anita K. Mehta
    Emily M. Cheney
    Christina A. Hartl
    Constantia Pantelidou
    Madisson Oliwa
    Jessica A. Castrillon
    Jia-Ren Lin
    Katie E. Hurst
    Mateus de Oliveira Taveira
    Nathan T. Johnson
    William M. Oldham
    Marian Kalocsay
    Matthew J. Berberich
    Sarah A. Boswell
    Aditi Kothari
    Shawn Johnson
    Deborah A. Dillon
    Mikel Lipschitz
    Scott Rodig
    Sandro Santagata
    Judy E. Garber
    Nadine Tung
    José Yélamos
    Jessica E. Thaxton
    Elizabeth A. Mittendorf
    Peter K. Sorger
    Geoffrey I. Shapiro
    Jennifer L. Guerriero
    Nature Cancer, 2021, 2 : 66 - 82
  • [6] Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer
    Mehta, Anita K.
    Cheney, Emily M.
    Hartl, Christina A.
    Pantelidou, Constantia
    Oliwa, Madisson
    Castrillon, Jessica A.
    Lin, Jia-Ren
    Hurst, Katie E.
    de Oliveira Taveira, Mateus
    Johnson, Nathan T.
    Oldham, William M.
    Kalocsay, Marian
    Berberich, Matthew J.
    Boswell, Sarah A.
    Kothari, Aditi
    Johnson, Shawn
    Dillon, Deborah A.
    Lipschitz, Mikel
    Rodig, Scott
    Santagata, Sandro
    Garber, Judy E.
    Tung, Nadine
    Yelamos, Jose
    Thaxton, Jessica E.
    Mittendorf, Elizabeth A.
    Sorger, Peter K.
    Shapiro, Geoffrey I.
    Guerriero, Jennifer L.
    NATURE CANCER, 2021, 2 (01) : 66 - +
  • [7] TARGETING IMMUNOSUPPRESSIVE MACROPHAGES OVERCOMES PARP-INHIBITOR RESISTANCE IN BRCA1-ASSOCIATED TRIPLE-NEGATIVE BREAST CANCER
    Mehta, Anita
    Cheney, Emily
    Hartl, Christina
    Pantelidou, Constantia
    Oliwa, Madison
    Castrillon, Jessica
    Lin, Jia-Ren
    Hurst, Katie
    Taveira, Mateus De Oliveira
    Johnson, Nathan
    Oldham, William
    Kalocsay, Marian
    Berberich, Matthew
    Boswell, Sarah
    Kothari, Aditi
    Johnson, Shawn
    Dillon, Deborah
    Lipschitz, Mikel
    Rodig, Scott
    Santagata, Sandro
    Garber, Judy
    Tung, Nadine
    Yelamos, Jose
    Thaxton, Jessica
    Mittendorf, Elizabeth
    Sorger, Peter
    Shapiro, Geoffrey
    Guerriero, Jennifer
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A512 - A512
  • [8] Inhibition of RPTOR overcomes resistance to EGFR inhibition in triple-negative breast cancer cells
    You, Kyu Sic
    Yi, Yong Weon
    Kwak, Sahng-June
    Seong, Yeon-Sun
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 52 (03) : 828 - 840
  • [9] A Novel Allosteric Inhibitor Targets PLK1 in Triple Negative Breast Cancer Cells
    Patel, Jankiben R.
    Thangavelu, Prasad
    Terrell, Renee M.
    Israel, Bridg'ette
    Sarkar, Arindam Basu
    Davidson, A. Michael
    Zhang, Kun
    Khupse, Rahul
    Tilghman, Syreeta L.
    BIOMOLECULES, 2022, 12 (04)
  • [10] Inhibition of Akt/mTOR pathway overcomes intrinsic resistance to dasatinib in triple-negative breast cancer
    Haga, Yuya
    Higashisaka, Kazuma
    Yang, Lili
    Sekine, Naoki
    Lin, Ying
    Tsujino, Hirofumi
    Nagano, Kazuya
    Tsutsumi, Yasuo
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 533 (04) : 672 - 678