Endoscopic resection for residual oesophageal neoplasia after definitive chemoradiotherapy

被引：0
|
作者：
Honing, Judith [1 ]
Koch, Arjun D. [1 ]
Siersema, Peter D. [1 ]
Spaander, Manon [1 ,2 ]
机构：
[1] Univ Med Ctr Rotterdam, Erasmus MC Canc Inst, Dept Gastroenterol & Hepatol, Rotterdam, Netherlands
[2] Erasmus Univ, Erasmus MC Canc Inst, Med Ctr, Dr Molewaterpl 40,POB 2040, NL-3000 CA Rotterdam, Netherlands
来源：
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY | 2024年 / 68卷
关键词：
Salvage; Endoscopic; Submucosal dissection; Definitive; Chemoradiotherapy; SQUAMOUS-CELL CARCINOMA; LOCAL FAILURE; NEOADJUVANT CHEMORADIOTHERAPY; SUBMUCOSAL DISSECTION; MUCOSAL RESECTION; SALVAGE TREATMENT; RANDOMIZED-TRIAL; CANCER; RECURRENCE; SURGERY;
D O I：
10.1016/j.bpg.2024.101885
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Definitive chemoradiation is the recommended treatment for locally advanced, irresectable oesophageal cancer and a valid alternative to neoadjuvant chemoradiotherapy (CRT) with surgery in oesophageal squamous cell cancer (OSCC) patients. In case of locoregional recurrence, salvage treatment can be considered in fit and resectable patients. Salvage surgery is a valid option but associated with significant morbidity. Therefore, for tumors confined to the mucosa or submucosal layers endoscopic resection is a good and less -invasive alternative. Over the last decade several case -series have demonstrated a high technical success rate of endoscopic treatment after definitive CRT. In this review we summarize the clinical outcomes and challenges of endoscopic treatment of early recurrence after definitive CRT in oesophageal cancer.
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页数：6
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