Classification of 2-node excitatory-inhibitory networks

被引:1
|
作者
Aguiar, Manuela [1 ,2 ]
Dias, Ana [3 ]
Stewart, Ian [4 ]
机构
[1] Univ Porto, Ctr Matemat Univ Porto CMUP, Fac Ciencias, Rua Campo Alegre S-N, P-4169007 Porto, Portugal
[2] Univ Porto, Fac Econ, Rua Dr Roberto Frias, P-4200464 Porto, Portugal
[3] Univ Porto, Ctr Matemat Univ Porto CMUP, Fac Ciencias, Dept Matemat, Rua Campo Alegre S-N, P-4169007 Porto, Portugal
[4] Univ Warwick, Math Inst, Coventry CV4 7AL, England
关键词
Excitatory-inhibitory network; Excitatory and inhibitory connections; ODE-equivalence; TOGGLE SWITCH; CONSTRUCTION; EQUIVALENCE; HOMEOSTASIS; SYNCHRONY; PATTERNS; BEHAVIOR; MOTIFS;
D O I
10.1016/j.mbs.2024.109205
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We classify connected 2-node excitatory-inhibitory networks under various conditions. We assume that, as well as for connections, there are two distinct node-types, excitatory and inhibitory. In our classification we consider four different types of excitatory-inhibitory networks: restricted, partially restricted, unrestricted and completely unrestricted. For each type we give two different classifications. Using results on ODE-equivalence and minimality, we classify the ODE-classes and present a minimal representative for each ODE-class. We also classify all the networks with valence <= 2 . These classifications are up to renumbering of nodes and the interchange of 'excitatory' and 'inhibitory' on nodes and arrows. These classifications constitute a first step towards analysing dynamics and bifurcations of excitatory-inhibitory networks. The results have potential applications to biological network models, especially neuronal networks, gene regulatory networks, and synthetic gene networks.
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页数:16
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