Tube-Like Copper Cobalt Oxide Anchored with Multiwalled Carbon Nanotube Nanocomposite Modified Glassy Carbon Electrode for the Electrochemical Detection of Nilutamide

被引:3
|
作者
Sivaji, Saravana Pandi [1 ]
Mariappan, Kiruthika [1 ]
Chen, Tse-Wei [2 ]
Chen, Shen-Ming [1 ]
Sivaramakrishnan, Vinothini [3 ]
Chiu, Te-Wei [3 ]
Elsadek, Mohamed Farouk [4 ]
Al-Mohaimeed, Amal M. [5 ]
Elshikh, Mohamed S. [6 ]
Yu, Jaysan [7 ]
机构
[1] Natl Taipei Univ Technol, Coll Engn, Dept Chem Engn & Biotechnol, Electroanal & Bioelectrochem Lab, Taipei 106, Taiwan
[2] Imperial Coll London, Dept Mat, London SW7 2AZ, England
[3] Natl Taipei Univ Technol, Dept Mat & Mineral Resources, Engn, Taipei 106, Taiwan
[4] King Saud Univ, Coll Sci, Dept Biochem, PO 2455, Riyadh 11451, Saudi Arabia
[5] King Saud Univ, Coll Sci, Dept Chem, POB 22452, Riyadh 11495, Saudi Arabia
[6] King Saud Univ, Coll Sci, Dept Bot & Microbiol, Riyadh 11451, Saudi Arabia
[7] Well Fore Special Wire Corp, Chung Li Ind Pk, Taoyuan, Taiwan
关键词
Nilutamide; Copper cobalt oxide; Multi-walled carbon nanotube; Sensitivity; Real sample analysis; SENSITIVE DETERMINATION; GRAPHENE OXIDE; CHLORAMPHENICOL; NANOSHEETS; PAPER; HONEY; MILK;
D O I
10.1149/1945-7111/ad4de3
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
Developing a precise and effective method to detect Nilutamide (NIL) is essential due to its contamination of the environment, which poses significant risks to human health and the biosphere. In this study, we employed a simple hydrothermal technique to create a nanocomposite of CuCo2O4 (copper cobalt oxide) and multi-walled carbon nanotube (MWCNT), which was then anchored onto a glassy carbon electrode for NIL detection. Various spectroscopic techniques were employed to confirm the structure of the nanomaterial, and its electrochemical properties were examined using cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. The CuCo2O4/MWCNT nanocomposite-modified electrode exhibited a wide linear detection range from 0.01 to 170 mu M, a high sensitivity of 1.50 mu A mu M-1 cm-2, a low detection limit of 0.01 mu M, outstanding stability, repeatability, and practical applicability for NIL detection. CuCo2O4/MWCNT decorated GCE applied for the electrochemical detection of Nilutamide detection. GCE/CuCo2O4/MWCNT electrode exhibited a wide linear detection range (0.01-170 mu M), a high sensitivity (1.50 mu A mu M-1 cm-2), and a low detection limit (0.01 mu M) GCE/CuCo2O4/MWCNT electrode performed outstanding stability, repeatability, and practical applicability. The practical applicability of the GCE/CuCo2O4/MWCNT electrode was tested in blood serum and urine samples.
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页数:13
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