PEDIATRIC PATIENTS WITH DIFFUSE MIDLINE GLIOMA DEMONSTRATE AN UNEXPECTED PREVALENCE OF GERMLINE VARIANTS IN HOMOLOGOUS RECOMBINATION GENES

被引：0

作者：

Mateos, Marion K. ^{[1
,2
]}

Ajuyah, Pamela ^{[2
]}

Fuentes-Bolanos, Noemi ^{[1
,2
]}

El Kamand, Sam ^{[2
]}

Barahona, Paulette ^{[2
,3
]}

Altekoester, Ann ^{[2
]}

Mayoh, Chelsea ^{[2
,3
]}

Holiday, Holly ^{[2
,3
]}

Liu, Jie ^{[2
]}

Cui, Louise ^{[2
]}

Pfaff, Elke ^{[4
,5
,6
,7
]}

Mackay, Alan ^{[8
]}

Resnick, Adam ^{[9
,10
]}

Pinese, Mark ^{[2
,3
]}

Lau, Loretta M. S. ^{[1
,2
]}

Khuong-Quang, Dong-Anh ^{[11
,12
]}

Dias, Kimberly ^{[2
]}

Goudie, Catherine ^{[13
,14
]}

Salkeld, Alison ^{[15
,16
]}

Rokita, Jo Lynne ^{[9
,10
]}

Jones, David T. W. ^{[4
,5
]}

Juretic, Nikoleta ^{[17
,18
]}

Hayden, Elisha ^{[2
]}

Pfister, Stefan M. ^{[4
,5
,6
,7
]}

Kramm, Christof M. ^{[19
]}

Blattner-Johnson, Mirjam ^{[4
,5
]}

Jabado, Nada

Tsoli, Maria ^{[2
,3
]}

Vittorio, Orazio ^{[2
,20
]}

Mueller, Sabine ^{[21
]}

Guo, Yiran ^{[9
]}

Tucker, Katherine ^{[1
,3
]}

Waszak, Sebastian M. ^{[22
,23
]}

Perreault, Sebastien ^{[24
]}

Jones, Chris ^{[8
]}

Wong-Erasmus, Marie ^{[2
]}

Cowley, Mark J. ^{[2
,3
]}

Ziegler, David S. ^{[1
,3
]}

机构：

[1] Sydney Childrens Hosp Randwick, Kids Canc Ctr, Sydney, NSW, Australia

[2] UNSW, Childrens Canc Inst, Lowy Canc Res Ctr, Sydney, NSW, Australia

[3] UNSW Sydney, Sch Clin Med, UNSW Med & Hlth, Discipline Paediat & Child Hlth, Sydney, NSW, Australia

[4] Hopp Childrens Canc Ctr Heidelberg KiTZ, German Canc Res Ctr DKFZ, Div Pediat Glioma Res, Heidelberg, Germany

[5] German Canc Consortium DKTK, Heidelberg, Germany

[6] Heidelberg Univ Hosp, Dept Pediat Oncol Hematol Immunol & Pulmonol, Heidelberg, Germany

[7] Natl Ctr Tumor Dis NCT, Heidelberg, Germany

[8] Inst Canc Res ICR, Div Mol Pathol, Sutton, Surrey, England

[9] Childrens Hosp Philadelphia, Ctr Data Driven Discovery Biomed, Philadelphia, PA USA

[10] Childrens Hosp Philadelphia, Div Neurosurg, Philadelphia, PA USA

[11] Royal Childrens Hosp, Murdoch Childrens Res Inst, Melbourne, Vic, Australia

[12] Royal Childrens Hosp, Childrens Canc Ctr, Parkville, Vic, Australia

[13] McGill Univ Hlth Ctr, Dept Pediat, Div Hematol Oncol, Montreal, PQ, Canada

[14] McGill Univ Hlth Ctr, Dept Child Hlth & Human Dev, Res Inst, Montreal, PQ, Canada

[15] Westmead Hosp, Crown Princess Mary Canc Ctr, Dept Radiat Oncol, Westmead, NSW, Australia

[16] Univ Sydney, Inst Med Phys, Sydney, NSW, Australia

[17] McGill Univ, Dept Pediat, Montreal, PQ, Canada

[18] McGill Univ Hlth Ctr, Res Inst, Montreal, PQ, Canada

[19] Univ Med Ctr Gottingen, Div Pediat Hematol & Oncol, Gottingen, Germany

[20] UNSW Sydney, Sch Biomed Sci, Sydney, NSW, Australia

[21] Univ Calif San Francisco, Dept Neurol Neurosurg & Pediat, San Francisco, CA USA

[22] Ecole Polytech Fed Lausanne, Swiss Inst Expt Canc Res, Sch Life Sci, Lausanne, Switzerland

[23] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA

[24] Univ Montreal, Ctr Hosp Univ Sainte Justine, Dept Neurosci, Montreal, PQ, Canada

来源：

NEURO-ONCOLOGY | 2024年 / 26卷

关键词：

D O I：

10.1093/neuonc/noae064.129

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

DIPG-76

引用

页数：2

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