Neutron spectroscopy for Boron Neutron Capture Therapy beams characterization
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作者:
Monti, V.
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Univ Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
INFN, Sez Torino, Via Pietro Giuria 1, I-10125 Turin, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Monti, V.
[1
,2
]
Costa, M.
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机构:
Univ Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
INFN, Sez Torino, Via Pietro Giuria 1, I-10125 Turin, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Costa, M.
[1
,2
]
Durisi, E.
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机构:
Univ Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
INFN, Sez Torino, Via Pietro Giuria 1, I-10125 Turin, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Durisi, E.
[1
,2
]
Mafucci, E.
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机构:
Univ Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
INFN, Sez Torino, Via Pietro Giuria 1, I-10125 Turin, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Mafucci, E.
[1
,2
]
Calamida, A.
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机构:Univ Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Calamida, A.
Campoy, A. I. Castro
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机构:
INFN, Lab Nazl Frascati, Via Enrico Fermi 40, I-00044 Frascati, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Campoy, A. I. Castro
[3
]
Fontanilla, A.
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机构:
INFN, Lab Nazl Frascati, Via Enrico Fermi 40, I-00044 Frascati, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Fontanilla, A.
[3
]
Russo, L.
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INFN, Lab Nazl Frascati, Via Enrico Fermi 40, I-00044 Frascati, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Russo, L.
[3
]
Bedogni, R.
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机构:
INFN, Lab Nazl Frascati, Via Enrico Fermi 40, I-00044 Frascati, ItalyUniv Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Bedogni, R.
[3
]
机构:
[1] Univ Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
[2] INFN, Sez Torino, Via Pietro Giuria 1, I-10125 Turin, Italy
Detector design and construction technologies and materials;
Instrumentation for hadron therapy;
NCT-WES;
SPECTROMETER;
D O I:
10.1088/1748-0221/19/05/C05036
中图分类号:
TH7 [仪器、仪表];
学科分类号:
0804 ;
080401 ;
081102 ;
摘要:
Boron Neutron Capture Therapy (BNCT) is a therapeutic treatment for malignant tumors that utilizes the nuclear reactions that happen when thermal neutrons are captured by boron-10 atoms to selectively destroy designated cells. Boron-10 atoms are biochemically accumulated inside the tumor target, which is then irradiated with thermal neutrons. In recent years, the possibility to obtain accelerator based intense neutron beams has given a boost to the diffusion of BNCT also in Europe, removing the need of nuclear reactors. In this contest, the monitoring and characterization of the epithermal neutron beams dedicated to BNCT becomes an important issue. The directional neutron spectrometer called NCT-WES (Neutron Capture Therapy Wide Energy Spectrometer) is a single moderator neutron spectrometer composed of a polyethylene cylinder embedding six semiconductor- based detectors positioned at different depths along the cylinder axes. The position of the six detectors is studied in order to maximize the response of each one in a selected neutron energy range. The unfolding of the six simultaneous readings allows to reconstruct the incoming neutron energy spectrum as in a parallelized Bonner Sphere System. A cylindrical collimator situated in the front of the spectrometer makes the instrument sensitive to neutrons coming only from a given direction, which allows to exclude the contribution of the room scattered radiation. The experimental validation of the spectrometer, obtained through several measuring campaigns, is reported and discussed.
机构:
Deutsches Krebsforschungsztr. (DKFZ), Abt. Med. Physik in der Radiologie, Heidelberg, Germany
Dept. of Med. Phys. in Radiol./E 020, Deutsches Krebsforschungsztr. (DKFZ), German Cancer Research Centre, Im Neuenheimer Feld 280, D - 69120 Heidelberg, GermanyDeutsches Krebsforschungsztr. (DKFZ), Abt. Med. Physik in der Radiologie, Heidelberg, Germany