Visceral Leishmaniasis: A Case Confirmed by Metagenomic Next-Generation Sequencing from Northwestern China

被引：0
|
作者：
Li, Ente [1 ,2 ]
Zhu, Qingfeng [3 ]
Lv, Ziman [1 ,2 ]
Xie, Songsong [3 ]
Zhang, Chunju [4 ]
Li, Wei [5 ]
Mi, Ligu [1 ,2 ]
Liu, Quan [6 ,7 ]
Wang, Yuanzhi [1 ,2 ]
Lu, Xiaobo [2 ]
机构：
[1] Shihezi Univ, Sch Med, Dept Basic Med, Shihezi 832002, Xinjiang Uygur, Peoples R China
[2] Shihezi Univ, Key Lab Prevent & Control Emerging Infect Dis & Pu, Xinjiang Prod & Construct Corps, Shihezi 832002, Xinjiang Uygur, Peoples R China
[3] Shihezi Univ Med Coll, Dept Nephropathy, Affiliated Hosp 1, Shihezi 832002, Xinjiang Uygur, Peoples R China
[4] Tumxuk Ctr Dis Prevent & Control, Tumxuk City 843806, Xinjiang Uygur, Peoples R China
[5] Tarim Univ, Sch Med, Dept Basic Med, Alaer 843300, Xinjiang Uygur, Peoples R China
[6] Jilin Univ, Dept Infect Dis, Hosp 1, Changchun 30061, Jilin, Peoples R China
[7] Jilin Univ, Ctr Infect Dis & Pathogen Biol, Key Lab Organ Regenerat & Transplantat, Key Lab Zoonot Dis,Minist Educ,Hosp 1, Changchun 30061, Jilin, Peoples R China
来源：
INFECTION AND DRUG RESISTANCE | 2024年 / 17卷
基金：
中国国家自然科学基金;
关键词：
Visceral leishmaniasis; Leishmania donovani; metagenomic next -generation sequencing; northwestern China;
D O I：
10.2147/IDR.S472172
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Visceral leishmaniasis (VL), also known as kala-azar. It is characterized by prolonged intermittent fever, anemia, splenomegaly, hepatomegaly, and skin darkening. VL is primarily endemic in regions, such as Brazil, East Africa, and India. However, Northern Xinjiang, which is located in northwestern China, is considered a low-incidence area for VL, contributing to its status as a neglected infectious disease. In this report, we present a case of VL caused by Leishmania donovani that was diagnosed using metagenomic next-generation sequencing (mNGS). This case underscores the diagnostic value of mNGS, particularly in regions with low incidence of VL.
引用
收藏
页码：3153 / 3158
页数：6
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