An Investigation on Optical, Larvacidal and Cytotoxicity Analysis of Sulfanilic Acid Single Crystal for Optical and Biomedical Applications

被引:0
|
作者
Manogaran, Punithavathi [1 ]
Jayapalan, Thirupathy [2 ]
Palanisamy, Revathi [3 ]
机构
[1] Marudhar Kesari Jain Coll Women Autonomous, Dept Biochem, Vaniyambadi 635751, Tamilnadu, India
[2] Marudhar Kesari Jain Coll Women Autonomous, Dept Phys, Vaniyambadi 635751, Tamilnadu, India
[3] Jamal Mohamed Coll Autonomous, Dept Phys, Trichy 620020, Tamilnadu, India
关键词
Crystal growth; Optical; Larvicidal; Cytotoxicity; COLORIMETRIC ASSAY; GROWTH; UV;
D O I
10.1007/s12013-024-01547-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Sulfanilic acid (SFA) crystal is well known as an effective material for photonic, electro-optical, harmonic generating and biomedical applications. A well-known nonlinear optical material, a high-quality SFA single crystal made utilizing the slow evaporation solution method (SEST) is the subject of this article. A 75 days development period yielded a transparent SFA single crystal measuring 5 x 5 x 2 mm3. The grown crystal used for different characterizations like Single crystal XRD used to find out the cell parameters. Fourier transforms infrared utilized to identify the band assignments. UV-Visible analysis used to detect the absorbance of the crystal and it is utilized for optical application. Photoluminescence studies utilized to recognize the excitation and emission of the grown crystal. Fluorescence used for determining the crystallinity and purity of the sample. The quantitative analysis is verified by using Elemental Dispersive Analysis by X-Rays. Scanning Electron Microscopy utilized to identify the structural and morphological characteristics. To the best of our knowledge, this paper is the first to provide the generated crystal that was used to analyze cytotoxicity and larvacidal activity. Assessment of larvicidal activity was used to ascertain the anti-malarial efficacy. We tested the items on MCF7-Human Breast cancer cell line and MCF7 Vero cells using the MTT Assay to identify the molecular basis of their cytotoxicity in vitro. Biological and optical are two areas that could benefit from the created crystal.
引用
收藏
页码:1139 / 1149
页数:11
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