Organic UV filters: Occurrence, risks and (anti-)progestogenic activities in samples from the Czech aquatic environment and their bioaccumulation in fish

被引：3

作者：

Amankwah, Beatrice Kyei ^{[1
]}

Sauer, Pavel ^{[1
]}

Grabicova, Katerina ^{[1
]}

von der Ohe, Peter C. ^{[2
]}

Ayikol, Nurhan Sultan ^{[3
]}

Kroupova, Hana Kocour ^{[1
]}

机构：

[1] Univ South Bohemia Ceske Budejovice, Fac Fisheries & Protect Waters, South Bohemian Res Ctr Aquaculture & Biodivers Hy, Zatisi 728-II, CZ-38925 Vodnany, Czech Republic

[2] UBA German Environm Agcy Umweltbundesamt, Worlitzer Pl 1, D-06844 Rosslau, Germany

[3] Ankara Univ, Grad Sch Hlth Sci, Dept Vet Pharmacol & Toxicol, Ankara, Turkiye

来源：

JOURNAL OF HAZARDOUS MATERIALS | 2024年 / 471卷

关键词：

Chemical analysis; Pollution; Solid-phase extraction; Organic micropollutants; in vitro bioassays; WASTE-WATER TREATMENT; PERSONAL CARE PRODUCTS; CHROMATOGRAPHY-MASS SPECTROMETRY; MULTIPLE HORMONAL ACTIVITIES; IN-VITRO BIOASSAYS; SURFACE WATERS; LIQUID-CHROMATOGRAPHY; ESTROGENIC ACTIVITY; TREATMENT PLANTS; 4-METHYLBENZYLIDENE CAMPHOR;

D O I：

10.1016/j.jhazmat.2024.134338

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The occurrence, environmental risks and contribution of organic UV filters to detected (anti-)progestogenic activities were examined in samples of wastewater treatment plant influents and effluents, various surface waters and fish from the Czech Republic. Of the 20 targeted UV filters, 15 were detected in the WWTP influent samples, 11 in the effluents, and 13 in the surface water samples. Benzophenone-3, benzophenone-4, and phenyl benzimidazole sulfonic acid (PBSA) were found in all water samples. Octocrylene, UV-327 and 4-methylbenzylidene camphor exceeded the risk quotient of 1 at some sites. In the anti-progestogenic CALUX assay, 10 out of the 20 targeted UV filters were active. Anti-progestogenic activities reaching up to 7.7 ng/L, 3.8 ng/L, and 4.5 ng/L mifepristone equivalents were detected in influents, effluents, and surface waters, respectively. UV filters were responsible for up to 37 % of anti-progestogenic activities in influents. Anti-progestogenic activities were also measured in fish tissues from the control pond and Podrou.zek (pond with the highest number of detected UV filters) and ranged from 2.2 to 9.5 and 1.9 to 8.6 ng/g dw mifepristone equivalents, respectively. However, only benzophenone was found in fish, but it does not display anti-progestogenic activity and thus could not explain the observed activities.

引用

页数：11