Smart Dressings and Their Applications in Chronic Wound Management

被引:0
|
作者
Li, Xiaodong [1 ]
Xue, Xiaodong [2 ]
Xie, Peilin [2 ]
机构
[1] Gansu Univ Chinese Med, Lanzhou Petrochem Co, Ctr Cosmet Surg, Gen Hosp,Affiliated Hosp 4, Lanzhou 730060, Gansu, Peoples R China
[2] Peoples Hosp Gansu Prov, Dept Plast Surg, Lanzhou 730000, Gansu, Peoples R China
关键词
Chronic wound; Smart dressings; pH sensor; Drug delivery; Wound oxygenation; HYDROGELS; BANDAGE;
D O I
10.1007/s12013-024-01402-w
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
During chronic wound healing, the inflammatory phase can endure for extended periods, heavily impeding or halting the process. Regular inspections and dressing changes are crucial. Modern dressings like hydrogels, hydrocolloids, and foam provide protection and an optimal healing environment. However, they have limitations in offering real-time wound bed status and healing rate. Evaluation relies heavily on direct observation, and passive dressings fail to identify subtle healing differences, preventing adaptive adjustments in biological factors and drug concentrations. In recent years, the clinical field recognizes the value of integrating intelligent diagnostic tools into wound dressings. By monitoring biomarkers linked to chronic wounds' inflammatory state, real-time data can be captured, reducing medical interventions and enabling more effective treatment plans. This fosters innovation in chronic wound care. Researchers have developed smart dressings with sensing, active drug delivery, and self-adjustment capabilities. These dressings detect inflammatory markers like temperature, pH, and oxygen content, enhancing drug bioavailability on the wound surface. As wound healing technology evolves, these smart dressings hold immense potential in chronic wound care and treatment. This comprehensive review updates our understanding on the role and mechanism of action of the smart dressings in chronic refractory wounds by summarizing and discussing the latest research progresses, including the intelligent monitoring of wound oxygen content, temperature, humidity, pH, infection, and enzyme kinetics; intelligent drug delivery triggered by temperature, pH, near-infrared, and electricity; as well as the intelligent self-adjustment of pressure and shape. The review also delves into the constraints and future perspectives of smart dressings in clinical settings, thereby advancing the development of smart wound dressings for chronic wound healing and their practical application in clinical practice.
引用
收藏
页码:1965 / 1977
页数:13
相关论文
共 50 条
  • [1] Advanced Dressings for Chronic Wound Management
    Mishra, Abhishek
    Kushare, Aniket
    Gupta, Munishwar Nath
    Ambre, Premlata
    ACS APPLIED BIO MATERIALS, 2024, 7 (05): : 2660 - 2676
  • [2] Smart wound dressings
    Korzeniewska, Ewa
    Szczesny, Artur
    Staniewski, Jakub
    Krawczyk, Andrzej
    Mroz, Jozef
    Serwach, Malgorzata
    PRZEGLAD ELEKTROTECHNICZNY, 2024, 100 (01): : 288 - 291
  • [3] Bioactive Wound Dressings for the Management of Chronic Wounds
    Georgescu, Mihaela
    Chifiriuc, Mariana C.
    Marutescu, Luminita
    Gheorghe, Irina
    Lazar, Veronica
    Bolocan, Alexandra
    Bertesteanu, Serban
    CURRENT ORGANIC CHEMISTRY, 2017, 21 (01) : 53 - 63
  • [4] Smart wound dressings for wound healing
    Dong, Ruonan
    Guo, Baolin
    NANO TODAY, 2021, 41
  • [5] The evolution of wound dressings: From traditional to smart dressings
    Ghomi, Erfan Rezvani
    Niazi, Mina
    Ramakrishna, Seeram
    POLYMERS FOR ADVANCED TECHNOLOGIES, 2023, 34 (02) : 520 - 530
  • [6] Wound dressings in chronic wound therapy
    Schreml, S.
    Klein, S. M.
    Babilas, P.
    Karrer, S.
    PHLEBOLOGIE, 2013, 42 (04) : 189 - 196
  • [7] Smart Dressings for Wound Healing: A Review
    Almeida, Isabella Barros
    Barretto Teixeira, Luciana Garcez
    de Carvalho, Fernanda Oliveira
    Silva, Erika Ramos
    Nunes, Paula Santos
    Viana dos Santos, Marcio Roberto
    de Souza Araujo, Adriano Antunes
    ADVANCES IN SKIN & WOUND CARE, 2021, 34 (02) : 1 - 8
  • [8] 'Smart' wound dressings for advanced wound care: a review
    O'Callaghan, Suzanne
    Galvin, Paul
    O'Mahony, Conor
    Moore, Zena
    Derwin, Rosemarie
    JOURNAL OF WOUND CARE, 2020, 29 (07) : 394 - 406
  • [9] Updates in Wound Management and Dressings
    Buote, Nicole J.
    VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 2022, 52 (02) : 289 - 315
  • [10] Surgical dressings and wound management
    Young, Trudie
    JOURNAL OF TISSUE VIABILITY, 2011, 20 (04) : 130 - 130