Comparison of physiological and behavioral nutrition-related factors in people with and without adolescent idiopathic scoliosis, from cohort data at 8 to 20 years

被引：1

作者：

Ng, Phoebe T. T. ^{[1
,2
]}

Tucker, Kylie ^{[1
]}

Zahir, Syeda Farah ^{[3
]}

Izatt, Maree T. ^{[4
]}

Straker, Leon ^{[5
]}

Claus, Andrew ^{[6
,7
]}

机构：

[1] Univ Queensland, Sch Biomed Sci, Lab Motor Control & Pain Res, St Lucia, Qld 4072, Australia

[2] KK Womens & Childrens Hosp, Physiotherapy Dept, 100 Bukit Timah Rd, Singapore 229899, Singapore

[3] Univ Queensland, Fac Med, Ctr Hlth Serv Res, Woolloongabba, Qld 4102, Australia

[4] Queensland Univ Technol, Ctr Childrens Hlth Res, Biomech & Spine Res Grp, South Brisbane, Qld 4101, Australia

[5] Curtin Univ, Sch Allied Hlth, Perth, WA 6102, Australia

[6] Univ Queensland, Sch Hlth & Rehabil Sci, St Lucia, Qld 4072, Australia

[7] Royal Brisbane & Womens Hosp, Tess Cramond Pain & Res Ctr, Herston, Qld 4029, Australia

来源：

JBMR PLUS | 2024年 / 8卷 / 03期

基金：

澳大利亚国家健康与医学研究理事会; 英国医学研究理事会; 加拿大健康研究院;

关键词：

adolescent idiopathic scoliosis; Raine study; nutrition; BMI; BMD; BONE-MINERAL DENSITY; EATING-DISORDERS; VITAMIN-D; BODY-COMPOSITION; ASSOCIATION; LEPTIN; MASS; PREVALENCE; GUIDELINES; OSTEOPENIA;

D O I：

10.1093/jbmrpl/ziad013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nutrition-related variables including lower body mass index (BMI), lower bone mineral density (BMD), altered body composition and hormone levels have been reported in adolescent idiopathic scoliosis (AIS). The aims of this study were to determine if physiological and behavioral nutrition-related factors differ between people with and without AIS, and to quantify their relationship with AIS, in unbiased cohort sample. BMI, presence of an eating disorder, leptin, adiponectin, BMD, vitamin D, lean mass, and fat mass were compared between those with and without AIS at ages 8, 10, 14, 17, and 20 years, and multiple logistic regression was performed between these variables and AIS. Lower total body BMD (median, 1.0 g/cm2 vs 1.1 g/cm2; p = .03) and lean mass (median, 38.8 kg vs 46.0 kg; p = .04) at age 20 years were observed in those with AIS compared to those without scoliosis. At age 20, the odds of AIS were 3.23 times higher for adolescents with an eating disorder compared to those with no eating disorder (95% CI, 1.02-8.63) when adjusted for BMI. Every 1 kg/m2 increase in BMI decreased the odds of AIS by 0.88 times (95% CI, 0.76-0.98), after adjusting for eating disorder diagnosis. In conclusion, lower BMI in mid-adolescence and presence of eating disorder outcomes, lower BMD, and lower lean mass in late adolescence were associated with the presence of AIS. Current data do not explain the mechanisms for these associations but suggest that serum leptin, adiponectin, and vitamin D are unlikely to be contributing factors. Conclusive determination of the prevalence of eating disorders in AIS will require further studies with larger sample sizes. Children and teenagers with scoliosis (sideways spinal curvature) may have poor nutritional health, which could impact their scoliosis. This study examined the differences in certain nutritional factors in young people with and without scoliosis. Young people with scoliosis were slightly more likely to be skinnier, have an eating problem, and have weaker bones and less muscle than those without scoliosis. Graphical Abstract

引用

页数：11