Orange fruit peels from PDO varieties of Ribera (Sicily, Italy): An insight into the chemistry and bioactivity of volatile and non-volatile secondary metabolites extracted using a microwave-assisted method

被引：4

作者：

Peron, Gregorio ^{[1
]}

Bernabe, Giulia ^{[2
]}

Marcheluzzo, Sara ^{[3
]}

Zengin, Gokhan ^{[4
]}

Sinan, Kouadio Ibrahime ^{[4
]}

Hosek, Jan ^{[5
,6
]}

Treml, Jakub ^{[6
]}

Kaja, Ignis ^{[5
,6
]}

Paccagnella, Michela ^{[3
]}

Brun, Paola ^{[2
]}

Castagliuolo, Ignazio ^{[2
]}

Zancato, Mirella ^{[3
]}

Dall'Acqua, Stefano ^{[3
]}

机构：

[1] Univ Brescia, Dept Mol & Translat Med DMMT, Viale Europa 11, I-25123 Brescia, Italy

[2] Univ Padua, Dept Mol Med, Via Gabelli 63, I-35121 Padua, Italy

[3] Univ Padua, Dept Pharmaceut & Pharmacol Sci, Via Marzolo 5, I-35131 Padua, Italy

[4] Selcuk Univ, Sci Fac, Dept Biol, TR-42130 Konya, Turkiye

[5] Vet Res Inst, Hudcova 296-70, CZ-62100 Brno, Czech Republic

[6] Masaryk Univ, Fac Pharm, Dept Mol Pharm, Palackeho tr 1946-1, CZ-61200 Brno, Czech Republic

来源：

JOURNAL OF FUNCTIONAL FOODS | 2024年 / 116卷

关键词：

Orange fruit peels; Volatile metabolites; Secondary metabolites; Antioxidants; Antimicrobials; ESSENTIAL OILS; ANTIOXIDANT ACTIVITY; HYDRO-DISTILLATION; SWEET ORANGES; CITRUS PEELS; CONSTITUENTS; GREEN;

D O I：

10.1016/j.jff.2024.106147

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Peels of Washington Navel (WAS), Navelina (NAV), and Vaniglia Apireno (VAN) orange fruits from Ribera (Sicily, Italy) represent abundant by-products of the Italian agro-food sector. In this work, volatile (VE) and nonvolatile (NVE) extracts were obtained from fresh peels using a microwave-assisted protocol, and were characterized for their content in secondary metabolites and bioactivity. VEs exerted antibacterial activity against different pathogens, and were toxic on Caco2 cells. Their main component was limonene (>85 %). NVEs inhibited tyrosinase, amylase, and glucosidase in vitro, and exerted significant antioxidant effects on THP-1 XBlue cells. They showed also anti-inflammatory properties, by decreasing NF-kappa B activity in LPS-stimulated cells. Putative molecular effectors were highlighted by multivariate correlation analysis. Overall, NVEs may represent novel sustainable nutraceutical ingredients with anti-inflammatory and metabolic properties, and can be obtained by using eco-sustainable approaches. Our results will encourage the reuse of by-products of the orange processing chain and will contribute to increase its circularity in the future.

引用

页数：11