Amniotic band syndrome

Amniotic banding sequence is a congenital disorder caused by early rupture of the amnion resulting in the development of amniotic bands that become attached or entangled in the fetus and generate a spectrum of fetal anomalies (disruption, deformity and/or malformation). Its incidence varies from 1 in 1,200 to 1 in 15,000 live births and would be responsible for 1/70 fetal deaths. The prognosis depends on the extent of the defects, which can range from minor anomalies to lethal ones such as umbilical cord constriction, causing fetal death or spontaneous abortions. We present the case of a patient with prenatal diagnosis of amniotic bands with severe deformities - asymmetry of the skull, exposure of brain tissue, amelia of the upper extremity, malposition of the lower extremities - emphasizing the importance of early diagnosis of this pathology in order to define timely procedures.