Serial Bronchoalveolar Lavage Fluid Aspergillus Galactomannan and Treatment Response in Invasive Pulmonary Aspergillosis

被引：2
|
作者：
Friedman, Daniel Z. P. [1 ,2 ,7 ]
Theel, Elitza S. [3 ]
Walker, Randall C. [1 ]
Vikram, Holenarasipur R. [4 ]
Razonable, Raymund R. [1 ,5 ]
Vergidis, Paschalis [1 ,5 ,6 ]
机构：
[1] Mayo Clin, Sect Infect Dis, Dept Med, Rochester, MN USA
[2] Univ Chicago, Sect Infect Dis & Publ Hlth, Chicago, IL USA
[3] Mayo Clin, Dept Lab Med & Pathol, Div Clin Microbiol, Rochester, MN USA
[4] Mayo Clin, Div Infect Dis, Phoenix, AZ USA
[5] Mayo Clin, William J von Liebig Ctr Transplantat & Clin Regen, Rochester, MN USA
[6] Mayo Clin, 200 First St SW, Rochester, MN 55905 USA
[7] Univ Chicago, 5841 S Maryland Ave, Chicago, IL 60637 USA
来源：
OPEN FORUM INFECTIOUS DISEASES | 2024年 / 11卷 / 04期
关键词：
aspergillosis; bronchoscopy; galactomannan; hematopoietic stem cell transplant; solid organ transplant; DIAGNOSIS;
D O I：
10.1093/ofid/ofae114
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We studied patients diagnosed with aspergillosis based on positive bronchoalveolar lavage (BAL) Aspergillus galactomannan (GM) who had follow-up BAL sampling within 180 days. GM trend and clinical outcome were concordant in only 60% (30/50). While useful for the initial diagnosis, BAL GM trending does not always correlate with treatment response.
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页数：4
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