Protein Engineering of Lactate Oxidase

被引:0
|
作者
Belyaeva, E. D. [1 ]
Komarova, N. V. [1 ]
Kuznetsov, A. E. [1 ]
机构
[1] Russian Acad Sci, Inst Nanotechnol Microelect, Moscow 119991, Russia
关键词
lactate oxidase; enzymes; lactate; diagnostics; mutations; AEROCOCCUS-VIRIDANS; ACTIVE-SITE; (S)-MANDELATE DEHYDROGENASE; AMPEROMETRIC BIOSENSOR; PSEUDOMONAS-PUTIDA; SUBSTRATE-BINDING; MECHANISM; THERMOSTABILITY; INTERFERENCE; REACTIVITY;
D O I
10.3103/S0027131424700032
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Lactate oxidase is a practically important enzyme widely used to detect L-lactate in medical diagnostics and in the food industry. This review summarizes the results of protein engineering of lactate oxidases to clarify the underlying mechanism of action of the enzyme and to improve its performance properties.
引用
收藏
页码:127 / 132
页数:6
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