Catalyst-Free Three-Component Synthesis of Novel Tetrahydrospiro[indole-3,3′-pyrazole] Derivatives

被引：0

作者：

Sankar, G. ^{[1
]}

Vinoth, N. ^{[1
]}

Kavishree, V. ^{[1
]}

Lalitha, A. ^{[1
]}

机构：

[1] Periyar Univ, Dept Chem, Salem 636011, Tamil Nadu, India

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 60卷 / 04期

关键词：

three-component condensation; tetrahydrospiro[indole-3,3 '-pyrazole; green synthesis; catalyst-free;

D O I：

10.1134/S1070428024040213

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of new tetrahydrospiro[indole-3,3 '-pyrazole]-4 '-carboxylate derivatives were synthesized by three-component reaction of substituted isatins, phenylhydrazines, and active methylene compounds in water without a catalyst at room temperature. The synthesized compounds were characterized by IR, H-1, C-13 NMR, and HRMS techniques.

引用

页码：717 / 722

页数：6

共 50 条

[1] Catalyst-Free Three-Component Synthesis of Spirobenzimidazolidines Bearing an Indole Scaffold
Moghaddam, F. Matloubi
Moafi, A.
Zamani, Z.
Daneshfar, M.
SYNLETT, 2018, 29 (17) : 2301 - 2305
[2] Catalyst-Free, Three-Component Synthesis of Amidinomaleimides
Swift-Ramirez, Wyatt R.
Whalen, Lindsay A.
Thompson, Lia K.
Shoemaker, Kaylee E.
Rubio, Aris R.
Weiss, Gregory A.
JOURNAL OF ORGANIC CHEMISTRY, 2024, 89 (18): : 13756 - 13761
[3] Catalyst-Free Three-Component Synthesis of α-Amino Phosphonates
Soliya, Sudha
Kuperkar, Ketan
Ashalu, Kashamalla Chinna
Naveen, Togati
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 13 (03)
[4] Catalyst-free three-component synthesis of hydroxyalkyltriazolylmethylidene barbiturates
Demina, Maria M.
Medvedeva, Alevtina S.
Vu, Tran D.
Larina, Lyudmila, I
Mitroshina, Inessa, V
Shemyakina, Olesya A.
MENDELEEV COMMUNICATIONS, 2019, 29 (06) : 655 - 657
[5] Catalyst-Free Three-Component Synthesis, Antibacterial, Antifungal, and Docking Studies of Spiroindoline Derivatives
Vinoth, Nangagoundan
Lalitha, Appaswami
POLYCYCLIC AROMATIC COMPOUNDS, 2022, 42 (02) : 517 - 533
[6] Synthesis of Thioamides by Catalyst-Free Three-Component Reactions in Water
Xu, Hualong
Deng, Hang
Li, Zhengkai
Xiang, Haifeng
Zhou, Xiangge
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 2013 (31) : 7054 - 7057
[7] Efficient Catalyst-Free One-Pot Three-Component Synthesis of Novel Spirooxindole Derivatives, and Their Cytotoxic Activities
Han, Chao
Zhang, Tao
Zhang, Anqi
Wang, Dandan
Shi, Weimin
Tao, Jingchao
SYNTHESIS-STUTTGART, 2014, 46 (10): : 1389 - 1398
[8] One-Pot and Three-Component Synthesis of Furopyridoquinoxaline Derivatives under Catalyst-Free Conditions
Zhang, Meimei
Wang, Jie
Liu, Jianquan
Wang, Xiangshan
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 37 (06) : 1565 - 1570
[9] Expedient, catalyst-free, three-component synthesis of fused tetrahydropyridines in water
Vinoth, Perumal
Prasad, P. S. Ram
Vivekanand, Thavaraj
Maheswari, C. Uma
Nagarajan, Subbiah
Carlos Menendez, J.
Sridharan, Vellaisamy
RSC ADVANCES, 2015, 5 (100) : 81881 - 81888
[10] Catalyst-Free Accelerated Three-Component Synthesis of Betti Bases in Microdroplets
Jin, Xiaoxiao
Wu, Yikang
Dai, Chengbiao
Sun, Jiannan
Ye, Meiying
Liu, Jinhua
Cheng, Heyong
CHEMPLUSCHEM, 2023, 88 (02):

← 1 2 3 4 5 →