Neural and Neural Crest-Derived Stem Cell Distribution in the Adult Human Dental Pulp

被引：0
|
作者：
Alzer, Heba [1 ]
Abu Shahin, Nisreen [2 ]
Alsoleihat, Firas [1 ,3 ]
机构：
[1] Univ Jordan, Sch Dent, Dept Restorat Dent, Amman 11942, Jordan
[2] Univ Jordan, Sch Med, Dept Pathol Microbiol & Forens Med, Amman 11942, Jordan
[3] Univ Petra, Fac Dent, Dept Restorat Dent & Basic Med Sci, Amman 11196, Jordan
来源：
INTERNATIONAL JOURNAL OF MORPHOLOGY | 2024年 / 42卷 / 02期
关键词：
NCAM1; Nestin; SNAIL/SLUG; SOX9; S100; Human dental pulp; Stem cells; Neural stem cells; Neural crest; SIDE POPULATION CELLS; IN-VITRO; TOOTH;
D O I：
暂无
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
Despite comprehensive studies and reports about the properties of dental pulp stem cells (DPSCs) in vitro, we still need to confirm whether these in vitro characteristics coincide with the nature of DPSCs in situ. The anatomical location of DPSCs populations in the dental pulp has yet to be investigated. Moreover, the mesenchymal DPSCs have been much more studied than the neural crest -derived DPSCs. In this study, well -recognized neural/neural crest stem cell markers NCAM1, Nestin, SNAIL/SLUG, SOX9, and S100 are being investigated by immunohistochemistry to localize the precise location of these populations of DPSCs within the human adult dental pulp. All previously mentioned markers were expressed in the dental pulp, and their intensity and location of expression were reported.
引用
收藏
页码：510 / 515
页数：6
相关论文
共 50 条
  • [1] Enrichment and Schwann Cell Differentiation of Neural Crest-derived Dental Pulp Stem Cells
    Al-Zer, Heba
    Apel, Christian
    Heiland, Max
    Friedrich, Reinhard E.
    Jung, Ole
    Kroeger, Nadja
    Eichhorn, Wolfgang
    Smeets, Ralf
    IN VIVO, 2015, 29 (03): : 319 - 326
  • [2] Sexual dimorphisms in adult human neural, mesoderm-derived, and neural crest-derived stem cells
    Greiner, Johannes F. W.
    Merten, Madlen
    Kaltschmidt, Christian
    Kaltschmidt, Barbara
    FEBS LETTERS, 2019, 593 (23) : 3338 - 3352
  • [3] Isolation and Characterization of Neural Crest-Derived Stem Cells from Dental Pulp of Neonatal Mice
    Janebodin, Kajohnkiart
    Horst, Orapin V.
    Ieronimakis, Nicholas
    Balasundaram, Gayathri
    Reesukumal, Kanit
    Pratumvinit, Busadee
    Reyes, Morayma
    PLOS ONE, 2011, 6 (11):
  • [4] Establishment and neural differentiation of neural crest-derived stem cells (NCSCs) from human dental pulp in serum-free conditions
    Solis-Castro, Oscar O.
    Boissonade, Fiona M.
    Rivolta, Marcelo N.
    STEM CELLS TRANSLATIONAL MEDICINE, 2020, 9 (11) : 1462 - 1476
  • [5] Origin and Clinical Applications of Neural Crest-Derived Dental Stem Cells
    Zhu, Yuan
    Zhang, Ping
    Gu, Ran Li
    Liu, Yun Song
    Zhou, Yong Sheng
    CHINESE JOURNAL OF DENTAL RESEARCH, 2018, 21 (02): : 89 - 100
  • [6] Multipotent neural crest-derived stem cells in the adult mouse cornea
    Yoshdia, Satoru
    Shimmura, Shigeto
    Matsuzaki, Yumi
    Okano, Hideyuki
    Tsubota, Kazuo
    NEUROSCIENCE RESEARCH, 2008, 61 : S281 - S281
  • [7] Adult human neural crest-derived cells for articular cartilage repair
    Pelttari, Karoliina
    Pippenger, Benjamin
    Mumme, Marcus
    Feliciano, Sandra
    Scotti, Celeste
    Mainil-Varlet, Pierre
    Procino, Alfredo
    von Rechenberg, Brigitte
    Schwamborn, Thomas
    Jakob, Marcel
    Cillo, Clemente
    Barbero, Andrea
    Martin, Ivan
    SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (251)
  • [8] Culture bag systems for clinical applications of adult human neural crest-derived stem cells
    Greiner, Johannes F. W.
    Grunwald, Lena-Marie
    Mueller, Janine
    Sudhoff, Holger
    Widera, Darius
    Kaltschmidt, Christian
    Kaltschmidt, Barbara
    STEM CELL RESEARCH & THERAPY, 2014, 5
  • [9] Culture bag systems for clinical applications of adult human neural crest-derived stem cells
    Johannes FW Greiner
    Lena-Marie Grunwald
    Janine Müller
    Holger Sudhoff
    Darius Widera
    Christian Kaltschmidt
    Barbara Kaltschmidt
    Stem Cell Research & Therapy, 5
  • [10] SPINAL CORD INJURY-DERIVED MONOCYTES ALTER THE VIABILITY AND IMMUNOMODULATORY PHENOTYPE OF NEURAL CREST-DERIVED DENTAL PULP STEM
    Doig, R. O'Hare
    Jenkner, S.
    Grose, R.
    Lewis, M.
    Clark, J.
    Gronthos, S.
    JOURNAL OF NEUROTRAUMA, 2022, 39 (15-16) : A10 - A11
12345