Long-term survival after cardiac arrest in patients undergoing emergent coronary angiography

被引：2

作者：

Vidal-Cales, Pablo ^{[1
]}

-Paz, Luis Ortega ^{[2
]}

Brugaletta, Salvatore ^{[1
]}

Garcia, John ^{[1
,11
]}

Rodes-Cabau, Josep ^{[1
]}

Angiolillo, Dominick J. ^{[2
]}

Regueiro, Ander ^{[1
]}

Freixa, Xavier ^{[1
,7
]}

Abdul-Jawad, Omar ^{[1
]}

Cepas-Guillen, Pedro Luis ^{[1
]}

Andrea, Rut ^{[1
]}

de Diego, Oriol ^{[1
]}

Tizon-Marcos, Helena ^{[3
,4
]}

Tomas-Querol, Carlos ^{[5
]}

Gomez-Hospital, Joan Antoni ^{[6
]}

Carrillo, Xavier ^{[7
]}

Rojas, Sergio ^{[9
]}

Munoz-Camacho, Juan Francisco ^{[10
]}

Garcia-Picart, Joan ^{[11
]}

Cardena, Merida ^{[8
]}

Lidon, Rosa Maria ^{[12
]}

Sabate, Manel ^{[1
,13
]}

机构：

[1] Hosp Clin Barcelona, Cardiovasc Clin Inst, Inst Invest Biomed August Pi i Sunyer, Barcelona, Spain

[2] Univ Florida, Coll Med, Div Cardiol, Jacksonville, FL USA

[3] Hosp Mar, Cardiol Dept, Barcelona, Spain

[4] Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, C Monforte de Lemos 3 5,Pabellon,11, Madrid 28029, Spain

[5] Hosp Arnau Vilanova, Cardiol Dept, IRBLleida, Lleida, Spain

[6] Hosp Bellvitge Princeps Espanya, Cardiol Dept, Barcelona, Spain

[7] Hosp Badalona Germans Trias & Pujol, Cardiol Dept, Barcelona, Spain

[8] Hosp Josep Trueta, Cardiol Dept, Girona, Spain

[9] Hosp Univ Tarragona Joan XXIII, Cardiol Dept, Tarragona, Spain

[10] Univ Barcelona, Cardiol Dept, Terrassa, Barcelona, Spain

[11] Hosp Santa Creu & Sant Pau, Cardiol Dept, Barcelona, Spain

[12] Vall Dhebron Hosp, Cardiol Dept, Barcelona, Spain

[13] Hosp Clin Barcelona, Clin Cardiovasc Inst, Inst Invest Biomed August Pi Sunyer IDIBAPS, Dept Cardiol, C Villarroel 170, Barcelona 08036, Spain

来源：

CARDIOVASCULAR REVASCULARIZATION MEDICINE | 2024年 / 60卷

关键词：

Hypothermia; induced; Targeted temperature management; Mortality; Cardiac arrest; Out -of -hospital cardiac arrest; in -hospital cardiac; arrest; Percutaneous coronary intervention; EUROPEAN RESUSCITATION COUNCIL; CARE MEDICINE GUIDELINES; THERAPEUTIC HYPOTHERMIA; SOCIETY; MANAGEMENT; CARDIOLOGY;

D O I：

10.1016/j.carrev.2023.09.008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: To determine long-term survival of patients after cardiac arrest undergoing emergent coronary angiography and therapeutic hypothermia. Methods: We analysed data from patients treated within the regional STEMI Network from January 2015 to December 2020. The primary endpoint was all-cause mortality at median follow-up. Secondary endpoints were periprocedural complications (arrhythmias, pulmonary edema, cardiogenic shock, mechanical complication, stent thrombosis, reinfarction, bleeding) and 6-month all-cause death. A landmark analysis was performed, studying two time periods; 0-6 months and beyond 6 months. Results: From a total of 24,125 patients in the regional STEMI network, 494 patients who suffered from cardiac arrest were included and divided into two groups: treated with (n = 119) and without therapeutic hypothermia (n = 375). At median follow-up (16.0 [0.2-33.3] months), there was no difference in the adjusted mortality rate between groups (51.3 % with hypothermia vs 48.0 % without hypothermia; HRadj1.08 95%CI [0.77-1.53]; p = 0.659). There was a higher frequency of bleeding in the hypothermia group (6.7 % vs 1.1 %; ORadj 7.99 95%CI [2.05-31.2]; p = 0.002), without difference for the rest of periprocedural complications. At 6-month follow-up, adjusted all-cause mortality rate was similar between groups (46.2 % with hypothermia vs 44.5 % without hypothermia; HRadj1.02 95%CI [0.71-1.47]; p = 0.900). Also, no differences were observed in the adjusted mortality rate between 6 months and median follow-up (9.4 % with hypothermia vs 6.3 % without hypothermia; HRadj2.02 95%CI [0.69-5.92]; p = 0.200). Conclusions: In a large cohort of patients with cardiac arrest within a regional STEMI network, those treated with therapeutic hypothermia did not improve long-term survival compared to those without hypothermia.

引用

页码：18 / 26

页数：9