Catalytic thiomethylation of indoles

被引：0
|
作者：
Akhmetova, V. R. [1 ]
Leont'ev, D. V. [1 ]
Akhmadiev, N. S. [1 ]
Paramonov, E. A. [1 ]
机构：
[1] Russian Acad Sci, Inst Petrochemistry & Catalysis, Ufa Fed Res Ctr, 141 prosp Oktyabrya, Ufa 450075, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2024年 / 73卷 / 07期
关键词：
indole; tryptophan; cysteine; mercaptans; formaldehyde; multicomponent reaction; thiomethylation; DERIVATIVES;
D O I：
10.1007/s11172-024-4315-6
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The catalysis of direct thiomethylation of 1H-indole and tryptophan under the action of the formaldehyde-mercaptan reagent system in the presence of acids and bases, phosphorus oxide and the oxidative system I2/NaOH was studied. A mechanism for the catalysis of the multicomponent thiomethylation reaction was proposed based on the results of mass spectrometric study of intermediate compounds.
引用
收藏
页码：1962 / 1967
页数：6
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