IMPORTANCE OF THE AROMATIC RING IN ADRENERGIC AMINES .5. NON-AROMATIC ANALOGS OF PHENYLETHANOLAMINE AS INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE - ROLE OF HYDROPHOBIC AND STERIC INTERACTIONS

被引：32

作者：

VINCEK, WC ^{[1
]}

ALDRICH, CS ^{[1
]}

BORCHARDT, RT ^{[1
]}

GRUNEWALD, GL ^{[1
]}

机构：

[1] UNIV KANSAS,DEPT MED EDUC,LAWRENCE,KS 66045

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1981年 / 24卷 / 01期

关键词：

D O I：

10.1021/jm00133a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：7 / 12

页数：6

共 16 条

[1] IMPORTANCE OF THE AROMATIC RING IN ADRENERGIC AMINES .6. NON-AROMATIC ANALOGS OF PHENYLETHANOLAMINE AS INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE - ROLE OF PI-ELECTRONIC AND STERIC INTERACTIONS
DAVIS, DP
BORCHARDT, RT
GRUNEWALD, GL
JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (01) : 12 - 16
[2] IMPORTANCE OF AROMATIC RING IN ADRENERGIC AMINES - NON-AROMATIC ANALOGUES OF PHENYLETHANOLAMINE AS SUBSTRATES FOR PHENYLETHANOLAMINE N-METHYLTRANSFERASE
GRUNEWALD, GL
GRINDEL, JM
VINCEK, WC
BORCHARDT, RT
MOLECULAR PHARMACOLOGY, 1975, 11 (05) : 694 - 699
[3] NON-AROMATIC ANALOGS OF PHENYLETHANOLAMINE (PEA) AS SUBSTRATES AND INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE (PNMT)
BORCHARDT, RT
GRUNEWALD, GL
ALDRICH, CS
VINCEK, WC
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1977, 173 (MAR20): : 21 - 21
[4] QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF NON-AROMATIC ANALOGS OF ETHANOLAMINE AS INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE
SINGH, P
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1985, 35 (01): : 21 - 23
[5] CONFORMATIONAL AND STERIC ASPECTS OF PHENYLETHANOLAMINE AND PHENYLETHYLAMINE ANALOGS AS SUBSTRATES OR INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE
GRUNEWALD, GL
YE, QH
SALL, DJ
CRISCIONE, KR
WISE, B
MOLECULAR PHARMACOLOGY, 1989, 35 (01) : 93 - 97
[6] IMPORTANCE OF THE AROMATIC RING IN ADRENERGIC AMINES .7. COMPARISON OF THE STEREOSELECTIVITY OF NOREPINEPHRINE N-METHYLTRANSFERASE FOR AROMATIC VS NON-AROMATIC SUBSTRATES AND INHIBITORS
RAFFERTY, MF
WILSON, DS
MONN, JA
KRASS, P
BORCHARDT, RT
GRUNEWALD, GL
JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (10) : 1198 - 1204
[7] IMPORTANCE OF AROMATIC RING IN ADRENERGIC AMINES - SOME NON-AROMATIC ANALOGS OF PHENETHANOLAMINES
GRUNEWALD, GL
GRINDEL, JM
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1975, (169): : 55 - 55
[8] IMPORTANCE OF AROMATIC RING IN ADRENERGIC AMINES .2. SYNTHESIS AND ADRENERGIC ACTIVITY OF SOME NON-AROMATIC 6-MEMBERED AND 8-MEMBERED RING ANALOGS OF BETA-PHENYLETHANOLAMINE
GRUNEWALD, GL
GRINDEL, JM
PATIL, PN
SALMAN, KN
JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (01) : 10 - 16
[9] CONFORMATIONAL PREFERENCES OF AMPHETAMINE ANALOGS FOR INHIBITION OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE - CONFORMATIONALLY DEFINED ADRENERGIC AGENTS .5.
GRUNEWALD, GL
BORCHARDT, RT
RAFFERTY, MF
KRASS, P
MOLECULAR PHARMACOLOGY, 1981, 20 (02) : 377 - 381
[10] DIFFERENTIAL CARDIOVASCULAR-RESPONSES TO NON-AROMATIC INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE (PNMT) IN INDIRECT TAIL-CUFF METHOD AND DIRECT BLOOD-PRESSURE MEASUREMENT
YOURICK, DL
TESSEL, RE
FEDERATION PROCEEDINGS, 1985, 44 (05) : 1645 - 1645

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