TARGETED GENE-EXPRESSION

The ability to introduce foreign genes into the germ line and the successful expression of the inserted gene in a specific tissue of the transgenic animal have created a further series of opportunities in the field of Developmental Biology. ThiS review will consider the methods for introducing genes into animals, review experiments to target expression in the mammary gland. Particular emphasis will be placed upon the experiments aimed to study the consequences of oncogene expression in the mammary gland and to the production of specific pharmaceutical proteins in the milk of farm animals.