REGULATION OF IGE SYNTHESIS BY CYTOKINES

被引：108
作者：
DEVRIES, JE
GAUCHAT, JF
AVERSA, GG
PUNNONEN, J
GASCAN, H
YSSEL, H
机构：
[1] DNAX Research Institute, Palo Alto, CA
来源：
CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 06期
关键词：
D O I：
10.1016/S0952-7915(05)80003-2
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Considerable progress has been made in our understanding of the mechanisms underlying regulation of human IgE synthesis. Interleukin-4 induces IgE production specifically, but costimulatory signals provided by T cells are required. Other cytokines modulate interleukin-4-induced IgE synthesis. The roles of T cells and cytokines in regulating IgE switching are discussed.
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收藏
页码：851 / 858
页数：8
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