From the legacy of an original disciplinary approach, as the Dependence theory and its Marxian critics, or the neo-structural economic theory founded by The Economic Commission for Latin America (ECLA), the Latin-American social sciences deny the Anglo-European centered approaches, in the way of reaffirming its own critical thinking, including the neo-colonial practices. The challenge for this critical thinking is to be, simultaneously, cosmopolitan and Latin American's one. In this process, the Latin-American social thinking is regaining its own originality and its vigorous proposals, thanks to a rich south-south dialogue, that implies a global character of its reflections and the questioning of its universal references. Although neither classical nor western Marxism are hegemonic within critical theory, the (neo) Marxism enriched with criticism of the coloniality of power, the theory of World-System, critical geopolitics and political ecology recover the field of critical theory in key founder of an epochal thinking time. Epistemological debates with post-structuralism and postmodern approaches configure various recent developments in critical theory.