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Technion Israel Inst Technol, Technion Integrated Canc Ctr, Rappaport Fac Med & Res Inst, Dept Genet & Dev Biol, IL-31096 Haifa, Israel Technion Israel Inst Technol, Technion Integrated Canc Ctr, Rappaport Fac Med & Res Inst, Dept Genet & Dev Biol, IL-31096 Haifa, Israel