CONSERVED REGIONS IN ORF1 PUTATIVE PROTEIN PRODUCTS OF MOBILE ELEMENTS AND RETROVIRAL PROTEINS ENCODED BY GENE GAG

被引：0

作者：

KANAPIN, AA ^{[1
]}

IVANOV, VA ^{[1
]}

ILIN, YV ^{[1
]}

机构：

[1] RUSSIAN ACAD SCI,VA ENGELHARDT MOLEC BIOL INST,MOSCOW 117984,RUSSIA

来源：

MOLECULAR BIOLOGY | 1995年 / 29卷 / 03期

关键词：

RETROVIRUSES; MOBILE ELEMENTS; GAG GENE;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Computer analysis of protein structure was used to assess the homology between. ORF1 putative protein products of mobile elements and the retroviral proteins encoded by the gag gene. Nucleotide and amino acid sequences of 113 retrotransposons were analyzed. Homologous domains were found in processed capsid and nucleocapsid proteins encoded by gag (22 and 17 amino acids, respectively). The regions related to the conserved domains of retroviruses were identified in the ORF1 putative protein products of several mobile elements. Multiple alignment revealed a conserved domain in the ORF1 products of mobile elements and p19 matrix protein of several retroviruses, which differed from the known sites and the abovementioned conserved regions of GAG. This region varies from one class of mobile elements to another, but is apparently conserved within each class. The secondary structure of this region corresponds to alpha-helix.

引用

页码：296 / 300

页数：5

共 6 条

[1] REGIONS OF 3D SIMILARITY IN POTENTIAL ORF1 PRODUCTS OF MOBILE GENETIC ELEMENTS OF DIFFERENT CLASSES
KANAPIN, A
BRODSKY, L
ILYIN, Y
PROTEIN ENGINEERING, 1993, 6 : 128 - 128
[2] Identification of two new antigen epitopes on the putative capsid protein encoded by torque teno sus virus type 1 ORF1
Liu, Jianbo
Zhang, Long
Huang, Liping
Wei, Yanwu
Wu, Hongli
Liu, Changming
VETERINARY MICROBIOLOGY, 2013, 167 (3-4) : 372 - 382
[3] A CONSERVED FAMILY OF NUCLEAR PROTEINS CONTAINING STRUCTURAL ELEMENTS OF THE FINGER PROTEIN ENCODED BY KRUPPEL, A DROSOPHILA SEGMENTATION GENE
SCHUH, R
AICHER, W
GAUL, U
COTE, S
PREISS, A
MAIER, D
SEIFERT, E
NAUBER, U
SCHRODER, C
KEMLER, R
JACKLE, H
CELL, 1986, 47 (06) : 1025 - 1032
[4] A putative protein structurally related to zygote arrest 1 (Zar1), Zar1-like, is encoded by a novel gene conserved in the vertebrate lineage
Sangiorgio, Lorenzo
Strumbo, Bice
Brevini, Tiziana A. L.
Ronchi, Severino
Simonic, Tatjana
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2008, 150 (02): : 233 - 239
[5] Imperfect DNA mirror repeats in the gag gene of HIV-1 (HXB2) identify key functional domains and coincide with protein structural elements in each of the mature proteins
Dorothy M Lang
Virology Journal, 4
[6] RHO GENE-PRODUCTS, PUTATIVE SMALL GTP-BINDING PROTEINS, ARE IMPORTANT FOR ACTIVATION OF THE CAL1/CDC43 GENE-PRODUCT, A PROTEIN GERANYLGERANYLTRANSFERASE IN SACCHAROMYCES-CEREVISIAE
QADOTA, H
ISHII, I
FUJIYAMA, A
OHYA, Y
ANRAKU, Y
YEAST, 1992, 8 (09) : 735 - 741

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