DIASTEREOSELECTIVE CONJUGATE ADDITION OF AMMONIA IN THE SYNTHESIS OF CHIRAL PYRROLIDINES

被引：21
|
作者：
ROBINA, I [1 ]
GEARING, RP [1 ]
BUCHANAN, JG [1 ]
WIGHTMAN, RH [1 ]
机构：
[1] HERIOT WATT UNIV,DEPT CHEM,EDINBURGH EH14 4AS,MIDLOTHIAN,SCOTLAND
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 09期
关键词：
D O I：
10.1039/p19900002622
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
threo-Selectivity in the conjugate addition of ammonia to 4,5-isopropylidenedioxypent-2-enoic esters has been exploited in a new synthesis of homochiral pyrrolidines; the origin of the diastereoselectivity is discussed.
引用
收藏
页码：2622 / 2624
页数：3
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