PATCH TESTING WITH THE SESQUITERPENE LACTONE MIX - A MARKER FOR CONTACT ALLERGY TO COMPOSITAE AND OTHER SESQUITERPENE-LACTONE-CONTAINING PLANTS

被引：68
|
作者：
DUCOMBS, G
BENEZRA, C
TALAGA, P
ANDERSEN, KE
BURROWS, D
CAMARASA, JG
DOOMSGOOSSENS, A
FROSCH, PJ
LACHAPELLE, JM
MENNE, T
RYCROFT, RJG
WHITE, IR
SHAW, S
WILKINSON, JD
机构：
[1] ST JOHNS HOSP DIS SKIN,LONDON WC2H 7BJ,ENGLAND
[2] WYCOMBE GEN HOSP,HIGH WYCOMBE,BUCKS,ENGLAND
[3] UNIV STRASBOURG 1,DERMATOL CLIN,DERMATOCHIM LAB,F-67070 STRASBOURG,FRANCE
[4] ROYAL VICTORIA HOSP,BELFAST BT12 6BA,NORTH IRELAND
[5] HOSP NOSTRA SENYORA DEL MAR,DEPT MED RES DERMATOL,BARCELONA,SPAIN
[6] CATHOLIC UNIV LEUVEN,B-3030 HEVERLE,BELGIUM
[7] UNIV HEIDELBERG,DEPT DERMATOL,W-6900 HEIDELBERG,GERMANY
[8] CATHOLIC UNIV LOUVAIN,UNITE DERMATOL PROFESS,B-1200 BRUSSELS,BELGIUM
[9] GENTOFTE HOSP,DK-2900 COPENHAGEN,DENMARK
来源：
CONTACT DERMATITIS | 1990年 / 22卷 / 05期
关键词：
alantolactone costunolide; allergic contact dermatitis; Compositae; dehydrocostunolide; Frullania; Lauraceae; mix; patch testing; patch testing technique; plants; sesquiterpene lactones;
D O I：
10.1111/j.1600-0536.1990.tb01590.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
6278 patients were patch tested with a sesquiterpene lactone mix (SL‐mix) in 10 European clinics. 4011 patients were tested only with 0.1% SL‐mix. 63 (approximately 1.5%) of whom were positive, with 26 (41%) of these cases being considered clinically relevant. There were no cases of active sensitization occurred though 5 eases of irritation were reported. 22 irritant reactions and 22 cases of active sensitization occurred when testing also with 1% and 0.33% concentrations of SL‐mix. SL‐mix 0.1% pet is shown to be an important patch test and many relevant sensitizations will be missed without routine screening with such a mix. Most patients with SL‐mix sensitivity presented with hand and/or face dermatitis, apparent photodermatitis or more generalised eczema. Copyright © 1990, Wiley Blackwell. All rights reserved
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页码：249 / 252
页数：4
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