HYPOLIPIDEMIC 2-[4-(1,1-DIMETHYLETHYL)PHENYL]-4H-3,1-BENZOXAZIN-4-ONES - STRUCTURE ACTIVITY RELATIONSHIPS OF A NOVEL SERIES OF HIGH-DENSITY LIPOPROTEIN ELEVATORS

被引：67
|
作者：
FENTON, G
NEWTON, CG
WYMAN, BM
BAGGE, P
DRON, DI
RIDDELL, D
JONES, GD
机构：
[1] RHONE POULEC LTD,DAGENHAM RES CTR,DEPT MED CHEM,RAINHAM RD S,DAGENHAM RM10 7XS,ESSEX,ENGLAND
[2] RHONE POULEC LTD,DAGENHAM RES CTR,DEPT BIOL RES,DAGENHAM RM10 7XS,ESSEX,ENGLAND
[3] RHONE POULEC LTD,DAGENHAM RES CTR,DEPT BIOPHARMACEUT RES,DAGENHAM RM10 7XS,ESSEX,ENGLAND
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 01期
关键词：
D O I：
10.1021/jm00121a047
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：265 / 272
页数：8
相关论文
共 50 条
  • [1] 4H-3,1-BENZOXAZIN-4-ONES METHOXY-SUBSTITUTED 2-(2-ARENSULPHONYLAMINOPNENYL( -4H-3,1-BENZOXAZIN-4-ONES
    LOSEVA, MV
    BOLOTIN, BM
    KRASOVIT.BM
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1971, (08): : 1028 - &
  • [2] THE SYNTHESIS OF A NOVEL SERIES OF SUBSTITUTED 2-PHENYL-4H-3,1-BENZOXAZIN-4-ONES
    PAVLIDIS, VH
    PERRY, PJ
    SYNTHETIC COMMUNICATIONS, 1994, 24 (04) : 533 - 548
  • [3] A facile synthesis of 2-[1-(dialkylamino)alkyl]-4H-3,1-benzoxazin-4-ones by the reaction of 1,1-dimethylethyl 2-isocyanobenzoates with N,N-dialkyliminium iodides
    Kobayashi, Kazuhiro
    Hashimoto, Hiroo
    Matsumoto, Mao
    Inouchi, Hiroki
    TETRAHEDRON, 2014, 70 (37) : 6398 - 6401
  • [4] STRUCTURE-ACTIVITY STUDIES ON 2-ARYL-4H-3,1-BENZOXAZIN-4-ONES
    HADFIELD, JA
    PAVLIDIS, VH
    MCGOWN, AT
    WHITWORTH, C
    PERRY, PJ
    FOX, BW
    ANTI-CANCER DRUGS, 1994, 5 (05) : 533 - 538
  • [5] 2-ARYL-SUBSTITUTED 4H-3,1-BENZOXAZIN-4-ONES AS NOVEL ACTIVE SUBSTANCES FOR THE CARDIOVASCULAR-SYSTEM
    ROSE, U
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1991, 28 (08) : 2005 - 2012
  • [6] Exploration of various solid forms of novel (1H-Benzimidazole, 2-[4-(1,1-dimethylethyl) phenyl])
    Rout, Smruti Rekha
    Kenguva, Gowtham
    Giri, Lopamudra
    Dandela, Rambabu
    RESULTS IN CHEMISTRY, 2023, 5
  • [7] Synthesis of 2-[(Z)-1-hydropolyfluoro-1-alkenyl]-4H-3, 1-benzoxazin-4-ones
    Liu, JT
    Lü, HJ
    JOURNAL OF FLUORINE CHEMISTRY, 2001, 111 (02) : 213 - 216
  • [8] Synthesis and reactions of 2-[α-(3,4-disubstituted phenacyl)-p-substituted styryl]-4H-3,1-benzoxazin-4-ones
    SOLIMAN
    Ahmed Youssef
    ATTIA
    Ibrahim Abd El-Mogoud
    SALEM
    Moneer Abdu Ibrahim
    El-SayedAhmed
    GABER
    Adel Mohy El-Deen
    ChineseJournalofChemistry, 1996, (05) : 437 - 446
  • [9] Femtosecond dynamics of intramolecular photoinduced proton transfer in N-substituted 2-(2-aminophenyl)-4H-3,1-benzoxazin-4-ones
    Khimich, M. N.
    Gostev, F. E.
    Shelaev, I. V.
    Sarkisov, O. M.
    Birgen, E. A.
    Bolotin, B. M.
    Uzhinov, B. M.
    HIGH ENERGY CHEMISTRY, 2010, 44 (06) : 482 - 491
  • [10] Femtosecond dynamics of intramolecular photoinduced proton transfer in N-substituted 2-(2-aminophenyl)-4H-3,1-benzoxazin-4-ones
    M. N. Khimich
    F. E. Gostev
    I. V. Shelaev
    O. M. Sarkisov
    E. A. Birgen
    B. M. Bolotin
    B. M. Uzhinov
    High Energy Chemistry, 2010, 44 : 482 - 491
12345