ION-MOLECULE REACTIONS IN THE GAS PHASE-IX - DIFFERENTIATION OF ENANTIOMERIC MENTHOLS USING A STEREOSPECIFIC SN2 PROCESS INDUCED BY A CHIRAL REAGENT

被引：26
|
作者：
TABET, JC
机构：
来源：
TETRAHEDRON | 1987年 / 43卷 / 15期
关键词：
D O I：
10.1016/S0040-4020(01)81632-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Stereospecific ion-molecule reactions of chiral reagents such as amino-alcohol with Mr, s, r enantiomeric alcohols (both methols with R- and S-hydroxylic groups, respectively) yield both diastereomeric (Mr, r, s + AsH - H2O)+ and (Ms, r, s + AsH - H2O)+ ions. This specific gas phase synthesis combined with Mass Spectrometry/Maas Spectrometry analysis was applied to differentiate enantiomeric alcohols. Indeed, respective MIKE/ CID spectra present differences in the daughter ion abundances which are useful for distinguishing between the initial alcohol configurations.
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收藏
页码：3413 / 3420
页数：8
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