HIGHLY REGIOSELECTIVE, (E)-STEREOSELECTIVE AND DIASTEREOSELECTIVE SN2' ADDITION OF ORGANOCUPRATES TO CHIRAL ALLYLIC CYCLIC CARBONATES

被引：25
|
作者：
KANG, SK
LEE, DH
SIM, HS
LIM, JS
机构：
[1] Department of Chemistry, Sung Kyun Kwan University, Suwon, 440-746, Natural Science Campus
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 01期
关键词：
D O I：
10.1016/S0040-4039(00)60065-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of the cyclic carbonates of acyclic vinyl diols with RCu(CN)Li.BF3, RCu(CN)MgBr-BF3, or RMgBr.CuI (cat) in THF at -78-degrees-C proceeded in S(N)2' fashion and resulted in the formation of alkylated (E)-allylic alcohols with remarkably high diastereoselectivity. This reaction represents an efficient 1, 3-chirality transfer method.
引用
收藏
页码：91 / 94
页数：4
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