A CONVENIENT ONE-POT SYNTHESIS OF 1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-10H-PYRIMIDO[5,4-B][1,4]-BENZOTHIAZINES

被引：0

作者：

AHLUWALIA, VK

AGGARWAL, R

KUMAR, R

机构：

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1994年 / 33卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 1,3-dimethylbarbituric acid (1) with N-bromosuccinimide followed by condensation with o-aminothiophenols (2a-d) results in the formation of 1,3-dimethyl-2, 4-dioxo-1, 2, 3, 4-tetrahydro-10H-pyri-mido[5,4-b][1,4]benzothiazines (3a-d). Further, N-alkylation of 3a-d with formaldehyde and piperidine gives the corresponding 1,3-dimethyl-2,4-dioxo-10-(N-piperidmomethyl-1, 2, 3, 4-tetrahydro-10H-pyrimido[5,4-b][1,4]benzothiazines (4a-d).

引用

页码：65 / 66

页数：2

共 50 条

[1] SMILES REARRANGEMENT .16. A CONVENIENT SYNTHESIS OF 2,4-DIOXO-1,2,3,4-TETRAHYDRO-10H-PYRIMIDO[5,4-B][1,4]BENZOTHIAZINES (DIHYDRO-5-THIAISOALLOXAZINES) VIA THERMAL SMILES REARRANGEMENT OF 6-(2-AMINOPHENYLTHIO)-5-BROMOURACILS
MAKI, Y
SAKO, M
TANABE, M
SUZUKI, M
SYNTHESIS-STUTTGART, 1981, (06): : 462 - 464
[2] SYNTHESIS AND ALKYLATION OF 10H-PYRIMIDO[5,4-B][1,4]BENZOTHIAZINES
FENNER, H
ROSSLER, HH
GRAUERT, RW
ARCHIV DER PHARMAZIE, 1981, 314 (12) : 1015 - 1022
[3] REDOX REACTIONS OF 10H-PYRIMIDO[5,4-B][1,4]BENZOTHIAZINES
FENNER, H
ROSSLER, HH
GRAUERT, RW
ARCHIV DER PHARMAZIE, 1981, 314 (12) : 1023 - 1030
[4] 5-ARYLTHIOPYRIMIDINES .3. CYCLIZATION OF 4-HYDROXY DERIVATIVES TO 10H-PYRIMIDO[5,4-B][1,4]BENZOTHIAZINES (1,3-DIAZAPHENOTHIAZINES)
ROTH, B
SCHLOEMER, LA
JOURNAL OF ORGANIC CHEMISTRY, 1963, 28 (10): : 2659 - &
[5] 2-Aminopyridinium 5-(5-chloro-2,4-dinitrophenyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-6-olate
Manickkam, Vaduganathan
Kalaivani, Doraisamyraja
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O3475 - U247
[6] A CONVENIENT ONE-POT PREPARATION OF 1,3-DISUBSTITUTED 6-METHYLTHIO-2,4-DIOXO-1,2,3,4-TETRAHYDRO-1,3,5-TRIAZINES [6-METHYLTHIO-1,3,5-TRIAZINE-2,4(1H,3H)-DIONES]
SANEMITSU, Y
SYNTHESIS-STUTTGART, 1985, (04): : 429 - 430
[7] A CONVENIENT ONE-POT SYNTHESIS OF 5-ARYL-7-METHYL-1,2,3,4-TETRAHYDRO-2,4-DIOXO-5H-PYRANO[2,3-D]PYRIMIDINES
AHLUWALIA, VK
AGGARWAL, R
KUMAR, R
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1993, 32 (09): : 963 - 964
[8] Synthesis of α,ω-Bis(3-methyl- or 3,6-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-1-pyrimidinyl)alkanes
V. E. Semenov
V. D. Akamsin
V. S. Reznik
Russian Journal of General Chemistry, 2001, 71 : 1088 - 1090
[9] A one-pot synthesis of pyrazolo [3,4-b][1,4]oxazines
Raslan, MA
Abd El-Latif, FM
Otto, HH
Sadek, KU
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2000, 32 (03) : 276 - 279
[10] Synthesis of α,ω-bis(3-methyl- or 3,6-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-1-pyrimidinyl)alkanes
Semenov, VE
Akamsin, VD
Reznik, VS
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2001, 71 (07) : 1088 - 1090

← 1 2 3 4 5 →