ENZYMATIC DEHALOGENATION OF 4-CHLOROBENZOYL COENZYME-A IN ACINETOBACTER SP STRAIN 4-CB1

被引：22

作者：

COPLEY, SD ^{[1
]}

CROOKS, GP ^{[1
]}

机构：

[1] UNIV COLORADO,NOAA,COOPERAT INST RES ENVIRONM SCI,BOULDER,CO 80309

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 1992年 / 58卷 / 04期

关键词：

D O I：

10.1128/AEM.58.4.1385-1387.1992

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

4-Chlorobenzoate degradation in cell extracts of Acinetobacter sp. strain 4-CB1 occurs by initial synthesis of 4-chlorobenzoyl coenzyme A (4-chlorobenzoyl CoA) from 4-chlorobenzoate, CoA, and ATP. 4-Chlorobenzoyl CoA is dehalogenated to 4-hydroxybenzoyl CoA. Following the dehalogenation reaction, 4-hydroxybenzoyl CoA is hydrolyzed to 4-hydroxybenzoate and CoA. Possible roles for the CoA moiety in the dehalogenation reaction are discussed.

引用

页码：1385 / 1387

页数：3

共 19 条

[1] BACTERIAL DEHALOGENATION OF CHLOROBENZOATES AND COCULTURE BIODEGRADATION OF 4,4'-DICHLOROBIPHENYL [J].

ADRIAENS, P ;

KOHLER, HPE ;

KOHLERSTAUB, D ;

FOCHT, DD .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1989, 55 (04) :887-892

[2]

Ames BN., 1966, METHOD ENZYMOL, V8, P115, DOI DOI 10.1016/0076-6879(66)08014-5

[3] TISSUE SULFHYDRYL GROUPS [J].

ELLMAN, GL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) :70-77

[4] DEGRADATION OF 4-CHLOROBENZOIC ACID BY A PSEUDOMONAS SP [J].

KLAGES, U ;

LINGENS, F .

ZENTRALBLATT FUR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE I ABTEILUNG ORIGINALE C-ALLGEMEINE ANGEWANDTE UND OKOLOGISCHE MIKROBIOLOGIE, 1980, 1 (03) :215-223

[5] CO-METABOLISM OF POLYCHLORINATED-BIPHENYLS - ENHANCED TRANSFORMATION OF AROCLOR 1254 BY GROWING BACTERIAL-CELLS [J].

KOHLER, HPE ;

KOHLERSTAUB, D ;

FOCHT, DD .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1988, 54 (08) :1940-1945

[6] DEHALOGENATION OF 4-CHLOROBENZOATE BY 4-CHLOROBENZOATE DEHALOGENASE FROM PSEUDOMONAS SP CBS3 - AN ATP COENZYME-A DEPENDENT REACTION [J].

LOFFLER, F ;

MULLER, R ;

LINGENS, F .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 176 (03) :1106-1111

[7] DEGRADATION OF 4-CHLOROBENZOIC ACID BY ARTHROBACTER SP [J].

MARKS, TS ;

SMITH, ARW ;

QUIRK, AV .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1984, 48 (05) :1020-1025

[8]

MARKS TS, 1984, BIOCH BIOPHSY RES CO, V124, P609

[9]

MERKEL SM, 1989, J BACTERIOL, V171, P1

[10]

MIEYAL JJ, 1974, J BIOL CHEM, V249, P2633

← 1 2 →