IMMUNITY TO JELLYFISH VENOMS - SUPPRESSION OF VENOM-INDUCED IMMUNE-RESPONSES IN ULTRAVIOLET B-IRRADIATED MICE

被引:3
|
作者
MIURA, S
BURNETT, JW
AURELIAN, L
机构
[1] UNIV MARYLAND,SCH MED,DEPT DERMATOL,BALTIMORE,MD 21201
[2] UNIV MARYLAND,SCH MED,DEPT PHARMACOL & EXPTL THERAPEUT,BALTIMORE,MD 21201
关键词
D O I
10.1016/0041-0101(93)90207-Y
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Lymph node and spleen cells from mice immunized with sea nettle (Chrysaora quinquecirrha) venom exhibited a proliferative response after exposure to the homologous antigen or that of a related jellyfish, Physalia (Portuguese man-o'-war). Native venom was a more effective stimulant than heated, non-lethal venom. Ultraviolet light treatments administered to the skin either before or after venom sensitization suppressed the proliferative response of these internal immune cells.
引用
收藏
页码:1415 / 1422
页数:8
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