AGGRESSION IN HUMANS CORRELATES WITH CEREBROSPINAL-FLUID AMINE METABOLITES

被引：914
作者：
BROWN, GL
GOODWIN, FK
BALLENGER, JC
GOYER, PF
MAJOR, LF
机构：
[1] James C. Ballenger, M.D., is Clinical Associate, Section on Psychobiology, BPB, Bethesda, MD
来源：
PSYCHIATRY RESEARCH | 1979年 / 1卷 / 02期
关键词：
5HIAA; Aggression; CSF; MHPG;
D O I：
10.1016/0165-1781(79)90053-2
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Cerebrospinal fluid levels of the major central metabolites of serotonin (5HT), norepinephrine (NE), and dopamine (DA)-5-hydroxyindoleacetic acid (5HIAA), 3-methoxy-4-hydroxy-phenylglycol (MHPG), and homovanillic acid (HVA), respectively-were studied in a group of 26 age-similar military men with no history of major pyschiatric illness, but with various personality disorders and difficulties adjusting to military life. Independently scored history of aggressive behavior showed a significant negative correlation with 5HIAA (r = -0.78) and a significant positive correlation with MHPG (r = 0.64). © 1979.
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收藏
页码：131 / 139
页数：9
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