SWISS UNRELATED BONE-MARROW DONOR REGISTRY - 1ST RESULTS

被引：0
|
作者：
GRATWOHL, A
HELG, C
CHAPUIS, B
GMUR, J
JEANNET, M
KERN, M
TICHELLI, A
SPECK, B
SIGNER, E
WYSS, M
SEGER, R
MORELL, A
机构：
[1] HOP CANTONAL GENEVA,DEPT MED INTERNE,CH-1211 GENEVA 4,SWITZERLAND
[2] HOP CANTONAL GENEVA,NATL REFERENZLAB HISTOKOMPATIBILITAT,CH-1211 GENEVA 4,SWITZERLAND
[3] ZENT LAB SRK,SCHWEIZER REGISTER UNVERWANDTE KNOCHENMARKSSPENDER,BERN,SWITZERLAND
[4] KINDERSPITAL,BASEL,SWITZERLAND
[5] HOP ENFANTS,GENEVA,SWITZERLAND
[6] UNIV ZURICH,KINDERKLIN,CH-8006 ZURICH,SWITZERLAND
来源：
SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT | 1992年 / 122卷 / 30期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Bone marrow transplantation from the unrelated volunteer donor is today a realistic possibility for patients lacking an HLA-identical family donor. In 1988, the Swiss Unrelated Bone Marrow Donor Registry was founded to coordinate such bone marrow transplants and create the Swiss volunteer donor registry. Thus for a search has been initiated for 71 patients and 16 transplants have been performed. Donor and recipient were HLA-A-, -B-identical by serology and HLA-Dr-identical by DNA-oligotyping. 10 of the 16 patients are alive without signs of basic disease 2 weeks to 2 years and 4 months after the transplant. These results illustrate that unrelated donor transplantation, using careful selection criteria, is a realistic new therapeutic modality.
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页码：1117 / 1122
页数：6
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