KINETICS OF THE HELIX-COIL TRANSITION OF A POLYPEPTIDE WITH NONIONIC SIDE GROUPS, DERIVED FROM ULTRASONIC RELAXATION MEASUREMENTS

被引：82

作者：

GRUENEWALD, B ^{[1
]}

NICOLA, CU ^{[1
]}

LUSTIG, A ^{[1
]}

SCHWARZ, G ^{[1
]}

KLUMP, H ^{[1
]}

机构：

[1] UNIV FREIBURG,INST PHYS CHEM,D-7800 FREIBURG,FED REP GER

来源：

BIOPHYSICAL CHEMISTRY | 1979年 / 9卷 / 02期

关键词：

D O I：

10.1016/0301-4622(79)87008-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ultrasonic absorption and velocity dispersion curves have been measured in the temperature induced helix-coil transition range ofpoly-N5-(3-hydroxypropyl)-L-glutamine in a methanol/water mixture. The results clearly reflect an effect due to the kinetics of the confonnational conversion. A practically single relaxation time is observed which passes through a maximum when plotted versus the degree of transition. This maximum occurs at definitely less than 50% helix as predicted for by the theory for the comparatively short chain length involved here. The results are discussed in relation to previous theoretical and experimental findings. © 1979.

引用

页码：137 / 147

页数：11

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