A NEW SYNTHESIS OF N-SUBSTITUTED-1,2,3,4-TETRAHYDRO-4-PHENYLISOQUINOLIN-3-ONES

被引：5

作者：

COSKUN, N ^{[1
]}

SUMENGEN, D ^{[1
]}

机构：

[1] ULUDAG UNIV,DEPT CHEM,BURSA,TURKEY

来源：

SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 10期

关键词：

D O I：

10.1080/00397919308011228

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,2,3,4-Tetrahydro-4-phenylisoquinolin-3-ones 3 are obtained from appropriate N,N-disubstituted phenylacetamides 1, using lead tetraacetate ( LTA ) as oxidant and Lewis or proton acids as cyclizing agents. The methods for this conversion could be one stage ( method B or C ), or two stages ( method A ). The latter method was particularly developed to explain the mechanism of the reaction.

引用

页码：1393 / 1402

页数：10

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