9-(2-HYDROXYETHOXYMETHYL)GUANINE ACTIVITY AGAINST VIRUSES OF HERPES GROUP

被引：1170

作者：

SCHAEFFER, HJ ^{[1
]}

BEAUCHAMP, L ^{[1
]}

MIRANDA, PD ^{[1
]}

ELION, GB ^{[1
]}

BAUER, DJ ^{[1
]}

COLLINS, P ^{[1
]}

机构：

[1] WELLCOME RES LABS, BECKENHAM BR3 3BS, KENT, ENGLAND

来源：

NATURE | 1978年 / 272卷 / 5654期

关键词：

D O I：

10.1038/272583a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Of a series of nucleoside analogues synthesized, 9-(2-hydroxy-ethoxymethyl) guanine was found to have marked antiviral activity in animal models of herpes virus infections, associated with very low toxicity. © 1978 Nature Publishing Group.

引用

页码：583 / 585

页数：3

共 13 条

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