EFFECT OF LONG-TERM FLUORIDE ADMINISTRATION ON THYROID-HORMONES LEVEL BLOOD IN RATS

被引：0

作者：

BOBEK, S ^{[1
]}

KAHL, S ^{[1
]}

EWY, Z ^{[1
]}

机构：

[1] ACAD AGR KRAKOW, INST APPL PHYSIOL ANIM, PL-30059 KRAKOW, POLAND

来源：

ENDOCRINOLOGIA EXPERIMENTALIS | 1976年 / 10卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[Fluoride becomes a problem of fundamental importance considering a steadily increasing threat of natural environment contaminated with the industrial emission of fluoride.] The effect of 2 mo. fluoride administration (0.1 and 1.0 mg daily/rat) on thyroxine [T4] and triiodothyronine [T3] level in blood and T3-resin uptake ratio was investigated in rats. In addition, free T4 index was calculated from serum T4 level and T3-resin uptake ratio. Fluoride administration caused a decrease in T4 and T3 level in plasma a decrease in free T4 index values and an increase in T3-resin uptake ratio. Fluoride given continously to the rats apparently may influence the thyroid gland rather indirectly by changing thyroid hormone transportation in the blood.

引用

页码：289 / 295

页数：7

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